NCT00006328

Brief Summary

This study is intended to help doctors learn about the relationships between specific genetic makeup (gene markers) and the development of chronic rejection. This study is being done to see if there is a relationship between genetic patterns and the development of Chronic Allograft Nephropathy (CAN). Medical scientists also hope to learn more about how genetic differences between people determine their response to a drug or a disease by storing a small blood sample in a special "bank". This sample may be tested at some point in the future in an attempt to better understand the factors that may influence rejection, transplantation outcomes and transplant success rates.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 4, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 5, 2000

Completed
Last Updated

June 24, 2005

Status Verified

December 1, 2003

First QC Date

October 4, 2000

Last Update Submit

June 23, 2005

Conditions

Kidney Disease

Keywords

Chronic Allograft Nephropathy (CAN)Transplantation immunologyGeneticsGraft Rejection

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All subjects must be recipients of a renal allograft.
  • Study subjects must have evidence of biopsy-proven Chronic Allograft Nephropathy (CAN).
  • Control subjects must not have evidence of CAN.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Univ. of Michigan Health System

Ann Arbor, Michigan, 48109-0391,, United States

Location

MeSH Terms

Conditions

Kidney Diseases

Condition Hierarchy (Ancestors)

Urologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Design

Study Type
observational
Observational Model
NATURAL HISTORY
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

October 4, 2000

First Posted

October 5, 2000

Last Updated

June 24, 2005

Record last verified: 2003-12

Locations

US(1)