NCT00005746

Brief Summary

To test the effectiveness of a community site neighborhood health worker/nurse (NHW/N) case management strategy for coronary heart disease risk reduction compared with usual care in apparently healthy African American siblings of persons with documented premature coronary heart disease.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Apr 1998

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1998

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
2.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2003

Completed
Last Updated

February 18, 2016

Status Verified

May 1, 2005

First QC Date

May 25, 2000

Last Update Submit

February 17, 2016

Conditions

Cardiovascular DiseasesHeart DiseasesCoronary DiseaseCoronary Heart Disease Risk Reduction

Eligibility Criteria

Age30 Years - 59 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Healthy Black siblings of individuals with premature coronary disease. Over 60% were women. Sibs were eligible if they were aged between 30 and 59 years with no known history of CAD, no chronic glucocorticosteroid therapy, no autoimmune disease, no current cancer therapy, and no immediate life-threatening comorbidity.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (4)

  • Becker DM, Tuggle MB, Prentice MF. Building a gateway to promote cardiovascular health research in African-American communities: lessons and findings from the field. Am J Med Sci. 2001 Nov;322(5):288-93.

    PMID: 11721804BACKGROUND

  • Mora S, Yanek LR, Moy TF, Fallin MD, Becker LC, Becker DM. Interaction of body mass index and framingham risk score in predicting incident coronary disease in families. Circulation. 2005 Apr 19;111(15):1871-6. doi: 10.1161/01.CIR.0000161956.75255.7B.

    PMID: 15837938BACKGROUND

  • Becker DM, Yanek LR, Johnson WR Jr, Garrett D, Moy TF, Reynolds SS, Blumenthal RS, Vaidya D, Becker LC. Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease. Circulation. 2005 Mar 15;111(10):1298-304. doi: 10.1161/01.CIR.0000157734.97351.B2.

    PMID: 15769772BACKGROUND

  • Benton JL, Blumenthal RS, Becker DM, Yanek LR, Moy TF, Post W. Predictors of low-density lipoprotein particle size in a high-risk African-American population. Am J Cardiol. 2005 Jun 1;95(11):1320-3. doi: 10.1016/j.amjcard.2005.01.075.

    PMID: 15904636BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesCoronary Disease

Condition Hierarchy (Ancestors)

Myocardial IschemiaVascular Diseases

Study Officials

  • Diane Becker

    Johns Hopkins University

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

April 1, 1998

Study Completion

March 1, 2003

Last Updated

February 18, 2016

Record last verified: 2005-05