NCT00005433

Brief Summary

To examine the appropriateness of angiographic and ultrasound endpoints as predictors of subsequent clinical coronary events. Follow-up data from the Cholesterol Lowering in Atherosclerosis Study (CLAS) were used.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
188

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 1996

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1996

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 1997

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 1997

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
Last Updated

April 24, 2017

Status Verified

April 1, 2017

Enrollment Period

1 year

First QC Date

May 25, 2000

Last Update Submit

April 20, 2017

Conditions

Cardiovascular DiseasesCoronary DiseaseCoronary ArteriosclerosisHeart Diseases

Eligibility Criteria

Age40 Years - 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

188 nonsmoking, 40-59 year old men with previous coronary artery bypass graft surgery

Male Nonsmoker Prior coronary artery bypass graft surgery

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (3)

  • Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu CR, Liu CH, Azen SP. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med. 1998 Feb 15;128(4):262-9. doi: 10.7326/0003-4819-128-4-199802150-00002.

    PMID: 9471928BACKGROUND

  • Mack WJ, LaBree L, Liu C, Selzer RH, Hodis HN. Correlations between measures of atherosclerosis change using carotid ultrasonography and coronary angiography. Atherosclerosis. 2000 Jun;150(2):371-9. doi: 10.1016/s0021-9150(99)00383-4.

    PMID: 10856529BACKGROUND

  • Mack WJ, Xiang M, Selzer RH, Hodis HN. Serial quantitative coronary angiography and coronary events. Am Heart J. 2000 Jun;139(6):993-9. doi: 10.1067/mhj.2000.105702.

    PMID: 10827379BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesCoronary DiseaseCoronary Artery DiseaseHeart Diseases

Condition Hierarchy (Ancestors)

Myocardial IschemiaVascular DiseasesArteriosclerosisArterial Occlusive Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

April 1, 1996

Primary Completion

April 1, 1997

Study Completion

April 1, 1997

Last Updated

April 24, 2017

Record last verified: 2017-04

Data Sharing

IPD Sharing
Will not share