Carotid Atherosclerosis Follow-up Study

NCT00005189 | Completed

• 2 other identifiers: 1067R01HL035333
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

To determine whether the degree of carotid artery atherosclerosis, as measured by B-mode ultrasound, predicts the development of myocardial infarction, stroke, and all-cause mortality in patients with angiographically defined coronary status. Also, to quantify the rate of progression of carotid artery disease and to evaluate the risk factors associated with progression of carotid atherosclerosis.

Conditions

Cardiovascular Diseases; Carotid Artery Diseases; Myocardial Infarction; Coronary Disease; Heart Diseases; Cerebrovascular Accident

Eligibility Criteria

• Age: Up to 100 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• National Heart, Lung, and Blood Institute (NHLBI): lead

Related Publications (15)

• Crouse JR 3rd. Hypertriglyceridemia: a contraindication to the use of bile acid binding resins. Am J Med. 1987 Aug;83(2):243-8. doi: 10.1016/0002-9343(87)90692-9.

  PMID: 3618626 BACKGROUND

• Crouse JR, Toole JF, McKinney WM, Dignan MB, Howard G, Kahl FR, McMahan MR, Harpold GH. Risk factors for extracranial carotid artery atherosclerosis. Stroke. 1987 Nov-Dec;18(6):990-6. doi: 10.1161/01.str.18.6.990.

  PMID: 3686596 BACKGROUND

• Crouse JR III, Kahl FR, Ryu JE: Changes in Treatment Patterns of Hyperlipidemia Among Patients Undergoing Coronary Angiograph: How Fleeting is the Memory. Circulation, 76(suppl):IV-292, 1987

  BACKGROUND

• Ryu JE, Espeland MA, Kahl FR, Thompson CJ, Crouse JR: Adipose Distribution in Females is Associated with Coronary Disease. Circulation, 76(suppl):IV-396, 1987

  BACKGROUND

• Rubens J, Espeland MA, Ryu J, Harpold G, McKinney WM, Kahl FR, Toole JF, Crouse JR 3rd. Individual variation in susceptibility to extracranial carotid atherosclerosis. Arteriosclerosis. 1988 Jul-Aug;8(4):389-97. doi: 10.1161/01.atv.8.4.389.

  PMID: 3395275 BACKGROUND

• Tell GS, Crouse JR, Furberg CD. Relation between blood lipids, lipoproteins, and cerebrovascular atherosclerosis. A review. Stroke. 1988 Apr;19(4):423-30. doi: 10.1161/01.str.19.4.423.

  PMID: 3284015 BACKGROUND

• Ryu JE, Murros K, Espeland MA, Rubens J, McKinney WM, Toole JF, Crouse JR. Extracranial carotid atherosclerosis in black and white patients with transient ischemic attacks. Stroke. 1989 Sep;20(9):1133-7. doi: 10.1161/01.str.20.9.1133.

  PMID: 2672424 BACKGROUND

• Craven TE, Ryu JE, Espeland MA, Kahl FR, McKinney WM, Toole JF, McMahan MR, Thompson CJ, Heiss G, Crouse JR 3rd. Evaluation of the associations between carotid artery atherosclerosis and coronary artery stenosis. A case-control study. Circulation. 1990 Oct;82(4):1230-42. doi: 10.1161/01.cir.82.4.1230.

  PMID: 2205416 BACKGROUND

• Howard G, Ryu JE, Evans GW, McKinney WM, Toole JF, Murros KE, Crouse JR 3rd. Extracranial carotid atherosclerosis in patients with and without transient ischemic attacks and coronary artery disease. Arteriosclerosis. 1990 Sep-Oct;10(5):714-9. doi: 10.1161/01.atv.10.5.714.

  PMID: 2403298 BACKGROUND

• Crouse JR 3rd, Hagaman AP. Smoking cessation in relation to cardiac procedures. Am J Epidemiol. 1991 Oct 1;134(7):699-703. doi: 10.1093/oxfordjournals.aje.a116146.

  PMID: 1951275 BACKGROUND

• Crouse JR 3rd, Thompson CJ. An evaluation of methods for imaging and quantifying coronary and carotid lumen stenosis and atherosclerosis. Circulation. 1993 Mar;87(3 Suppl):II17-33.

  PMID: 8443919 BACKGROUND

• Terry JG, Howard G, Mercuri M, Bond MG, Crouse JR 3rd. Apolipoprotein E polymorphism is associated with segment-specific extracranial carotid artery intima-media thickening. Stroke. 1996 Oct;27(10):1755-9. doi: 10.1161/01.str.27.10.1755.

  PMID: 8841324 BACKGROUND

• Crouse JR 3rd, Craven TE, Hagaman AP, Bond MG. Association of coronary disease with segment-specific intimal-medial thickening of the extracranial carotid artery. Circulation. 1995 Sep 1;92(5):1141-7. doi: 10.1161/01.cir.92.5.1141.

  PMID: 7648658 BACKGROUND

• Espeland MA, Tang R, Terry JG, Davis DH, Mercuri M, Crouse JR 3rd. Associations of risk factors with segment-specific intimal-medial thickness of the extracranial carotid artery. Stroke. 1999 May;30(5):1047-55. doi: 10.1161/01.str.30.5.1047.

  PMID: 10229743 BACKGROUND

• Crouse JR 3rd, Tang R, Espeland MA, Terry JG, Morgan T, Mercuri M. Associations of extracranial carotid atherosclerosis progression with coronary status and risk factors in patients with and without coronary artery disease. Circulation. 2002 Oct 15;106(16):2061-6. doi: 10.1161/01.cir.0000033833.54884.34.

  PMID: 12379574 BACKGROUND

MeSH Terms

Conditions

Cardiovascular Diseases; Carotid Artery Diseases; Myocardial Infarction; Coronary Disease; Heart Diseases; Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Myocardial Ischemia; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Officials

• John Crouse

  Bowman Gray School of Medicine

Study Design

• Study Type: observational
• Sponsor Type: NIH

Study Record Dates

• First Submitted: May 25, 2000
• First Posted: May 26, 2000
• Study Start: July 1, 1986
• Study Completion: April 1, 1999
• Last Updated: May 13, 2016

Record last verified: 2002-11