NCT00005154

Brief Summary

To supplement the fourth National Health and Nutrition Examination Survey protocol to include data on the common heart, vascular, lung, and blood diseases.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jul 1981

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 1981

Completed
18.9 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
8.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
Last Updated

April 14, 2009

Status Verified

April 1, 2009

Enrollment Period

27.4 years

First QC Date

May 25, 2000

Last Update Submit

April 13, 2009

Conditions

Cardiovascular DiseasesCoronary DiseaseHeart DiseasesHypertensionBlood DiseaseLung Diseases

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (16)

  • Leaverton PE, Sorlie PD, Kleinman JC, Dannenberg AL, Ingster-Moore L, Kannel WB, Cornoni-Huntley JC. Representativeness of the Framingham risk model for coronary heart disease mortality: a comparison with a national cohort study. J Chronic Dis. 1987;40(8):775-84. doi: 10.1016/0021-9681(87)90129-9.

    PMID: 3597679BACKGROUND

  • Gillum RF, Makuc DM. Serum albumin, coronary heart disease, and death. Am Heart J. 1992 Feb;123(2):507-13. doi: 10.1016/0002-8703(92)90667-k.

    PMID: 1736588BACKGROUND

  • Gillum RF, Ingram DD, Makuc DM. White blood cell count, coronary heart disease, and death: the NHANES I Epidemiologic Follow-up Study. Am Heart J. 1993 Mar;125(3):855-63. doi: 10.1016/0002-8703(93)90181-8.

    PMID: 8438715BACKGROUND

  • Linn S, Fulwood R, Carroll M, Brook JG, Johnson C, Kalsbeek WD, Rifkind BM. Serum total cholesterol: HDL cholesterol ratios in US white and black adults by selected demographic and socioeconomic variables (HANES II). Am J Public Health. 1991 Aug;81(8):1038-43. doi: 10.2105/ajph.81.8.1038.

    PMID: 1853996BACKGROUND

  • Feibleib M, Rifkind B, Sempos C, et al: Methodological issues in the measurement of CVD risk factors: within-person variability in selected serum lipid measures - results from the Third National Health and Nutrition Examination Survey (NHANES III). Can J Cardiol, 9 (suppl D):87D-88D, 1993

    BACKGROUND

  • Johnson CL, Rifkind BM, Sempos CT, Carroll MD, Bachorik PS, Briefel RR, Gordon DJ, Burt VL, Brown CD, Lippel K, et al. Declining serum total cholesterol levels among US adults. The National Health and Nutrition Examination Surveys. JAMA. 1993 Jun 16;269(23):3002-8.

    PMID: 8501842BACKGROUND

  • Winkleby MA, Kraemer HC, Ahn DK, Varady AN. Ethnic and socioeconomic differences in cardiovascular disease risk factors: findings for women from the Third National Health and Nutrition Examination Survey, 1988-1994. JAMA. 1998 Jul 22-29;280(4):356-62. doi: 10.1001/jama.280.4.356.

    PMID: 9686553BACKGROUND

  • Burt VL, Cutler JA, Higgins M, Horan MJ, Labarthe D, Whelton P, Brown C, Roccella EJ. Trends in the prevalence, awareness, treatment, and control of hypertension in the adult US population. Data from the health examination surveys, 1960 to 1991. Hypertension. 1995 Jul;26(1):60-9. doi: 10.1161/01.hyp.26.1.60.

    PMID: 7607734BACKGROUND

  • Andersen RE, Crespo CJ, Bartlett SJ, Cheskin LJ, Pratt M. Relationship of physical activity and television watching with body weight and level of fatness among children: results from the Third National Health and Nutrition Examination Survey. JAMA. 1998 Mar 25;279(12):938-42. doi: 10.1001/jama.279.12.938.

    PMID: 9544768BACKGROUND

  • Gillum RF, Mussolino ME, Sempos CT. Baseline serum total cholesterol and coronary heart disease incidence in African-American women (the NHANES I epidemiologic follow-up study). National Health and Nutrition Examination Survey. Am J Cardiol. 1998 May 15;81(10):1246-9. doi: 10.1016/s0002-9149(98)00122-2.

    PMID: 9604962BACKGROUND

  • Vargas CM, Ingram DD, Gillum RF. Incidence of hypertension and educational attainment: the NHANES I epidemiologic followup study. First National Health and Nutrition Examination Survey. Am J Epidemiol. 2000 Aug 1;152(3):272-8. doi: 10.1093/aje/152.3.272.

    PMID: 10933274BACKGROUND

  • Fields LE, Burt VL, Cutler JA, Hughes J, Roccella EJ, Sorlie P. The burden of adult hypertension in the United States 1999 to 2000: a rising tide. Hypertension. 2004 Oct;44(4):398-404. doi: 10.1161/01.HYP.0000142248.54761.56. Epub 2004 Aug 23.

    PMID: 15326093BACKGROUND

  • Carroll MD, Lacher DA, Sorlie PD, Cleeman JI, Gordon DJ, Wolz M, Grundy SM, Johnson CL. Trends in serum lipids and lipoproteins of adults, 1960-2002. JAMA. 2005 Oct 12;294(14):1773-81. doi: 10.1001/jama.294.14.1773.

    PMID: 16219880BACKGROUND

  • Xu Y, Yan Z, Liu L. Association between dietary intake of live microbes and chronic obstructive pulmonary disease: a cross-sectional study of NHANES 2007-2012. BMC Pulm Med. 2025 Jan 23;25(1):33. doi: 10.1186/s12890-024-03453-4.

    PMID: 39849413DERIVED

  • Lin Z, Zhu S, Cheng J, Lin Q, Lawrence WR, Zhang W, Huang Y, Chen Y, Gao Y. The mediating effect of engagement in physical activity over a 24-hour period on chronic disease and depression: Using compositional mediation model. J Affect Disord. 2022 Feb 15;299:264-272. doi: 10.1016/j.jad.2021.12.019. Epub 2021 Dec 11.

    PMID: 34902506DERIVED

  • Cameron NA, Petito LC, McCabe M, Allen NB, O'Brien MJ, Carnethon MR, Khan SS. Quantifying the Sex-Race/Ethnicity-Specific Burden of Obesity on Incident Diabetes Mellitus in the United States, 2001 to 2016: MESA and NHANES. J Am Heart Assoc. 2021 Feb 16;10(4):e018799. doi: 10.1161/JAHA.120.018799. Epub 2021 Feb 10.

    PMID: 33563002DERIVED

MeSH Terms

Conditions

Cardiovascular DiseasesCoronary DiseaseHeart DiseasesHypertensionHematologic DiseasesLung Diseases

Condition Hierarchy (Ancestors)

Myocardial IschemiaVascular DiseasesHemic and Lymphatic DiseasesRespiratory Tract Diseases

Study Officials

  • Paul Bachorik

    Johns Hopkins University

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

July 1, 1981

Primary Completion

December 1, 2008

Study Completion

December 1, 2008

Last Updated

April 14, 2009

Record last verified: 2009-04