NCT00004560

Brief Summary

To measure survival to hospital discharge of patients with out-of-hospital cardiac arrest in community units (e.g., apartment or office buildings, gated communities, sports venues, senior centers, shopping malls) served by trained non-medical responders using automated external defibrillators (AEDs), an approach called Public Access Defibrillation, compared to units receiving the traditional optimum community standard of care (i.e., rescuers trained to recognize a cardiac emergency, call 911, and initiate CPR).

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 1999

Typical duration for phase_3

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 1999

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

February 9, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 10, 2000

Completed
4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2004

Completed
Last Updated

April 14, 2016

Status Verified

November 1, 2005

First QC Date

February 9, 2000

Last Update Submit

April 13, 2016

Conditions

ArrhythmiaHeart ArrestHeart DiseasesMyocardial InfarctionVentricular FibrillationDeath, Sudden, Cardiac

Interventions

defibrillatorDEVICE

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (9)

  • Ornato JP, McBurnie MA, Nichol G, Salive M, Weisfeldt M, Riegel B, Christenson J, Terndrup T, Daya M; PAD Trial Investigators. The Public Access Defibrillation (PAD) trial: study design and rationale. Resuscitation. 2003 Feb;56(2):135-47. doi: 10.1016/s0300-9572(02)00442-2.

    PMID: 12589986BACKGROUND

  • Mosesso VN Jr, Brown LH, Greene HL, Schmidt TA, Aufderheide TP, Sayre MR, Stephens SW, Travers A, Craven RA, Weisfeldt ML; PAD Trial Investigators. Conducting research using the emergency exception from informed consent: the Public Access Defibrillation (PAD) Trial experience. Resuscitation. 2004 Apr;61(1):29-36. doi: 10.1016/j.resuscitation.2003.11.016.

    PMID: 15081178BACKGROUND

  • Sayre MR, Travers AH, Daya M, Greene HL, Salive ME, Vijayaraghavan K, Craven RA, Groh WJ, Hallstrom AP; PAD Investigators. Measuring survival rates from sudden cardiac arrest: the elusive definition. Resuscitation. 2004 Jul;62(1):25-34. doi: 10.1016/j.resuscitation.2004.02.007.

    PMID: 15246580BACKGROUND

  • Hallstrom AP, Ornato JP, Weisfeldt M, Travers A, Christenson J, McBurnie MA, Zalenski R, Becker LB, Schron EB, Proschan M; Public Access Defibrillation Trial Investigators. Public-access defibrillation and survival after out-of-hospital cardiac arrest. N Engl J Med. 2004 Aug 12;351(7):637-46. doi: 10.1056/NEJMoa040566.

    PMID: 15306665BACKGROUND

  • Nichol G, Wells GA, Kuntz K, Feeny D, Longstreth W, Mahoney B, Mann C, Lucas R, Henry M, Huszti E, Birnbaum A. Methodological design for economic evaluation in Public Access Defibrillation (PAD) trial. Am Heart J. 2005 Aug;150(2):202-8. doi: 10.1016/j.ahj.2004.09.034.

    PMID: 16086918BACKGROUND

  • Powell J, Van Ottingham L, Schron E. Public defibrillation: increased survival from a structured response system. J Cardiovasc Nurs. 2004 Nov-Dec;19(6):384-9. doi: 10.1097/00005082-200411000-00009.

    PMID: 15529059BACKGROUND

  • Richardson LD, Gunnels MD, Groh WJ, Peberdy MA, Pennington S, Wilets I, Campbell V, Van Ottingham L, McBurnie MA; PAD Trial Investigators. Implementation of community-based public access defibrillation in the PAD trial. Acad Emerg Med. 2005 Aug;12(8):688-97. doi: 10.1197/j.aem.2005.03.525.

    PMID: 16079421BACKGROUND

  • Birnbaum A, McBurnie MA, Powell J, Ottingham LV, Riegel B, Potts J, Hedges JR; PAD Investigators. Modeling instructor preferences for CPR and AED competence estimation. Resuscitation. 2005 Mar;64(3):333-9. doi: 10.1016/j.resuscitation.2004.08.019.

    PMID: 15733763BACKGROUND

  • Riegel B, Birnbaum A, Aufderheide TP, Thode HC Jr, Henry MC, Van Ottingham L, Swor R; PAD Investigators. Predictors of cardiopulmonary resuscitation and automated external defibrillator skill retention. Am Heart J. 2005 Nov;150(5):927-32. doi: 10.1016/j.ahj.2005.01.042.

    PMID: 16290965BACKGROUND

MeSH Terms

Conditions

Arrhythmias, CardiacHeart ArrestHeart DiseasesMyocardial InfarctionVentricular FibrillationDeath, Sudden, Cardiac

Interventions

Defibrillators

Condition Hierarchy (Ancestors)

Cardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and SymptomsMyocardial IschemiaVascular DiseasesInfarctionIschemiaNecrosisDeath, SuddenDeath

Intervention Hierarchy (Ancestors)

ElectrodesElectrical Equipment and SuppliesEquipment and Supplies

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

February 9, 2000

First Posted

February 10, 2000

Study Start

September 1, 1999

Study Completion

February 1, 2004

Last Updated

April 14, 2016

Record last verified: 2005-11