A Study to Compare Two Anti-HIV Drug Combinations
An Open Label, Randomized, Multicenter Study to Evaluate Fortovase (Saquinavir) SGC QD, Norvir (Ritonavir) QD Plus Two NRTIs Vs Sustiva (Efavirenz) QD Plus Two NRTIs in HIV Infected Patients
2 other identifiers
interventional
146
3 countries
26
Brief Summary
The purpose of this study is to compare 2 anti-HIV drug combinations.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_3 hiv-infections
26 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 1999
CompletedFirst Submitted
Initial submission to the registry
November 2, 1999
CompletedFirst Posted
Study publicly available on registry
August 31, 2001
CompletedJune 24, 2005
January 1, 2001
November 2, 1999
June 23, 2005
Conditions
Keywords
Interventions
Eligibility Criteria
You may qualify if:
- Patients may be eligible for this study if they:
- Are HIV-positive.
- Have a viral load of at least 5,000 copies/ml and a CD4 cell count of at least 75 cells/mm3.
- Are at least 18.
- Are able to complete the study.
You may not qualify if:
- Patients will not be eligible for this study if they:
- Have taken any anti-HIV medications for more than 2 weeks.
- Are pregnant or breast-feeding.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (26)
Univ of Alabama at Birmingham / AIDS Outpatient Clinic
Birmingham, Alabama, 35294, United States
St Mary's Med Ctr
Long Beach, California, 90813, United States
UCSF - San Francisco Gen Hosp
San Francisco, California, 94110, United States
Kaiser Foundation Hospital
San Francisco, California, 94118, United States
Georgetown Univ Med Ctr
Washington D.C., District of Columbia, 20007, United States
Physicans Home Service
Washington D.C., District of Columbia, 20037, United States
Associates in Research
Fort Myers, Florida, 33901, United States
Univ of Miami / Jackson Memorial Hosp
Miami, Florida, 33136, United States
Illinois Masonic Med Ctr
Chicago, Illinois, 606575147, United States
Saint Michael's Med Ctr / Dept of Infectious Diseases
Newark, New Jersey, 07102, United States
Infectious Disease Specialists of NJ
Union, New Jersey, 07083, United States
Elmhurst Hosp
Elmhurst, New York, 11373, United States
Queens Hospital Center
Jamaica, New York, 11432, United States
LIJMC
New Hyde Park, New York, 11040, United States
East Carolina Univ School of Medicine
Greenville, North Carolina, 27858, United States
Lehigh Valley Hosp
Allentown, Pennsylvania, 18105, United States
Burnside Clinic
Columbia, South Carolina, 29206, United States
Greenville Hospital System
Greenville, South Carolina, 29605, United States
Nicholas Bellos
Dallas, Texas, 75246, United States
Joseph Gathe
Houston, Texas, 77004, United States
Univ of Utah
Salt Lake City, Utah, 84132, United States
Univ of Washington / AIDS Clinical Trial Unit
Seattle, Washington, 98104, United States
Saint Paul's Hosp
Vancouver, British Columbia, Canada
Toronto Gen Hosp
Toronto, Ontario, Canada
Centre Hospitalier de la Universite de Montreal (CHUM)
Montreal, Quebec, Canada
Ponce Univ Hosp
Ponce, 00731, Puerto Rico
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
JSG Montaner
- STUDY CHAIR
Ann Collier
- STUDY CHAIR
Danielle Rouleau
- STUDY CHAIR
Michael Saag
- STUDY CHAIR
Paul Volberding
- STUDY CHAIR
Sharon Walmsley
- STUDY CHAIR
Nicholas Bellos
- STUDY CHAIR
Alfred Burnside
- STUDY CHAIR
Stephen Follansbee
- STUDY CHAIR
Joseph Gathe
- STUDY CHAIR
Bruce Hathaway
- STUDY CHAIR
Margaret Hoffman-Terry
- STUDY CHAIR
Jazila Mantis
- STUDY CHAIR
Joseph Masci
- STUDY CHAIR
Mahmoud Mustafa
- STUDY CHAIR
John Schrank
- STUDY CHAIR
Malte Schutz
- STUDY CHAIR
Leon Smith