Testing a Possible Cause of Reduced Ability of Children to Process Speech in Noise

NCT00001957 | Completed

• 2 other identifiers: 00001600-DC-0016
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to increase our understanding of the difficulty people have recognizing the spoken word, especially in noisy situations. Subjects must be between 12 and 18 years old with no history of voice disorder, autism, stuttering, aphasia, multiple sclerosis, traumatic brain injury, severe language disorders, and psychiatric disorders. Group A subjects must show reduced speech-in-noise scores and Group B subjects must demonstrate speech-in-noise scores within normal limits. The child will perform a series of hearing tasks that will take from 1.5 to 2 hours, with a break halfway through. A routine hearing test will be given. The child will sit in a sound-treated room wearing earphones and will depress a button in response to sound or to repeat words. The words may be in quiet or mixed with noise. In a test called "immitance," air pressure change and tones will be sent through a miniature probe in the ear for about 1 minute. TEOAE (transient-evoked otoacoustic emission) testing will test the inner ear with clicking sounds. At times, noise will be presented through a probe in the opposite ear. The child will listen to a series of recordings of speech in quiet and in noise and will be asked to repeat what is heard. These recordings will include monosyllabic words with some part of the sounds cut out; words presented with several voices speaking together; two words presented at the same time, one to each ear (child must repeat both words); and two sentences presented at the same time, one to each ear (child must repeat sentence presented to chosen ear). The only risk in this study is tiredness from listening.

Conditions

Central Auditory Disease; Healthy

Keywords

Ostoacoustic Emission; Central Auditory Processing; CAPD; Medial Olivocochlear Bundle; Speech Impediment

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Subjects selected will be between the ages of 12 and 18 years.
• All subjects must score within normal limits on measures of threshold sensitivity, speech recognition in quiet, middle ear function and TEOAEs to be included in the study.
• Group A subjects must be identified as having learning or attention problems in school and show show reduced scores on speech-in-noise tasks.
• Group B subjects must demonstrate speech-in-noise scores within normal limits.
• Groups will be matched for sex, age and handedness.

You may not qualify if:

• Subjects will be excluded for history of voice disorders, autism, stuttering, aphasia, multiple sclerosis, traumatic brain injury, severe language disorders and psychiatric disorders.
• Children who are being treated for hyperactivity disorder will be excluded.
• Children who are taking medication prescribed for hyperactivity, anxiety or depression may be excluded.
• Children younger than 12 will be excluded.

Sponsors & Collaborators

• National Institute on Deafness and Other Communication Disorders (NIDCD): lead

Study Sites (1)

National Institute on Deafness and Other Communication Disorders (NIDCD)

Bethesda, Maryland, 20892, United States

Location

Related Publications (3)

• Berlin CI, Hood LJ, Wen H, Szabo P, Cecola RP, Rigby P, Jackson DF. Contralateral suppression of non-linear click-evoked otoacoustic emissions. Hear Res. 1993 Dec;71(1-2):1-11. doi: 10.1016/0378-5955(93)90015-s.

  PMID: 8113128 BACKGROUND

• Collet L. Use of otoacoustic emissions to explore the medial olivocochlear system in humans. Br J Audiol. 1993 Apr;27(2):155-9. doi: 10.3109/03005369309077907.

  PMID: 8220283 BACKGROUND

• Collet L, Kemp DT, Veuillet E, Duclaux R, Moulin A, Morgon A. Effect of contralateral auditory stimuli on active cochlear micro-mechanical properties in human subjects. Hear Res. 1990 Jan;43(2-3):251-61. doi: 10.1016/0378-5955(90)90232-e.

  PMID: 2312416 BACKGROUND

MeSH Terms

Conditions

Auditory Diseases, Central; Speech Disorders

Condition Hierarchy (Ancestors)

Retrocochlear Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Sponsor Type: NIH

Study Record Dates

• First Submitted: January 18, 2000
• First Posted: January 19, 2000
• Study Start: November 1, 1999
• Study Completion: November 1, 2003
• Last Updated: March 4, 2008

Record last verified: 2003-11

Locations

US (1)