Study of Systemic Lupus Erythematosus

You may not qualify if:

• Concomitant medical problems which would confound the interpretation of studies gathered by this protocol. Included in this is the presence of HIV in the blood, active malignancies, or other significant medical conditions that may interferes with interpretation of some lupus studies.
• Concomitant medical, surgical or other conditions for which inadequate facilities are available to support their care at NIH
• Inability or unwillingness to comply with follow up requirements (e.g. distance, social, physical limitations)
• Any comorbidity of medical or psychological/psychiatric condition or treatment after reviewing of patients previous or outside medical records, that in the opinion of the Principal Investigator, would exclude the subjects from the research studies (e.g. Patient requiring urgent and/or acute medical care, surgical or other procedures)
• Unwilling to participate in research studies or to provide research samples or data
• Any concomitant medical problems or are taking medications which would confound the interpretation of studies they are considered for
• Subjects with a contraindication to MRI scanning will not receive the optional Cardiovascular MRI. These contraindications include subjects with the following devices:
• Central nervous system aneurysm clips unless it is labeled safe or conditional for MRI
• Implanted neural stimulator (e.g.TENS-Unit) unless it is labeled safe or conditional for MRI
• Implanted cardiac pacemaker or defibrillator unless it is labeled safe or conditional for MRI
• Cochlear or any type of ear implant unless it is labeled safe or conditional for MRI
• Ocular foreign body (e.g. metal shavings)
• Implanted Insulin pump or drug infusion device unless it is labeled safe or conditional for MRI
• Metal shrapnel or bullet unless cleared by plain x-ray as safe for MRI
• Pregnant or lactating women will be excluded from vascular studies.
• +3 more criteria