Diagnosis and Treatment of Patients With Cystic Fibrosis

NCT00001223 | Terminated

• 2 other identifiers: 87002987-DK-0029
• Study Type: observational
• Target: 79
• Locations: 1 country
• Sites: 1

Brief Summary

This is an omnibus protocol for studying patients with cystic fibrosis. The main purpose of the study is to obtain samples and data collected during standard clinical care for future research to expand knowledge of the natural history, clinical manifestations (phenotypes) and the genetic variants (genotypes) of cystic fibrosis.

Conditions

Cystic Fibrosis; Liver Disease or Abnormalities; Diabetes; Pancreatic Insufficiency (Exocrine and Endocrine)

Keywords

Cystic Fibrosis; Pancreatic Insufficiency; Bronchiectasis; Liver Disease; Natural History

Outcome Measures

Primary Outcomes (1)

• To develop a database and collection of samples obtained from patients with CF during their clinical care to allow for future research

  To develop a collection of samples and a database from patients with cystic fibrosis to be used in future research.

  end of study

Study Arms (2)

CF Patients

cystic fibrosis patients

CF Relatives

relatives of cystic fibrosis patients

Eligibility Criteria

• Age: 4 Years - 120 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Primarily local population but also any adult patient/relative that moves into the area, either through CF Foundation or relocating for personal reasons.

You may qualify if:

• Patients with known or suspected CF and family members of patients with CF.
• \>=4 years of age

You may not qualify if:

• Concomitant medical, psychiatric or other problems which might complicate interpretation of studies of CF, or for which we are unable to provide adequate care.

Sponsors & Collaborators

• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): lead

Study Sites (1)

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

Location

Related Links

• NIH Clinical Center Detailed Web Page

MeSH Terms

Conditions

Cystic Fibrosis; Liver Diseases; Congenital Abnormalities; Diabetes Mellitus; Exocrine Pancreatic Insufficiency; Bronchiectasis

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases; Lung Diseases; Respiratory Tract Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infant, Newborn, Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Bronchial Diseases

Study Officials

• Christopher Koh, M.D.

  National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 3, 1999
• First Posted: November 4, 1999
• Study Start: January 1, 1988
• Primary Completion: January 30, 2026
• Study Completion: January 30, 2026
• Last Updated: February 4, 2026

Record last verified: 2026-01

Locations

US (1)