Setting up a Blood Bank for Gene Therapy in HIV-Infected Infants
Establishment of a Cord Blood Bank for Gene Therapy in HIV-Infected Infants
1 other identifier
observational
200
1 country
8
Brief Summary
The purpose of this study is to set up a blood bank for infants who have HIV-positive mothers. This blood may be used in the future to treat the child if he/she turns out to be HIV-positive. Blood from the umbilical cord contains a certain kind of cell called a stem cell. Stem cells eventually turn into one of the many types of blood cells. If HIV infection can be prevented in these stem cells, then, when these stem cells are injected back into the infant, the new cells that develop will also be protected from HIV. This study will provide the blood needed to test whether this type of gene therapy is safe and effective.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
8 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 1997
CompletedFirst Submitted
Initial submission to the registry
November 2, 1999
CompletedFirst Posted
Study publicly available on registry
August 31, 2001
CompletedAugust 1, 2008
June 1, 2003
November 2, 1999
July 30, 2008
Conditions
Keywords
Eligibility Criteria
You may qualify if:
- You may be eligible for this study if you:
- Are HIV-positive.
You may not qualify if:
- Your child will not be eligible for this study if he/she:
- Is not expected to live more than 6 months.
- Weighs less than 3.3 pounds.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (8)
UCSD Med Ctr / Pediatrics / Clinical Sciences
La Jolla, California, 920930672, United States
Long Beach Memorial (Pediatric)
Long Beach, California, 90801, United States
Los Angeles County - USC Med Ctr
Los Angeles, California, 90033, United States
Cedars Sinai / UCLA Med Ctr
Los Angeles, California, 900481804, United States
UCLA Med Ctr / Pediatric
Los Angeles, California, 900951752, United States
Harbor - UCLA Med Ctr / UCLA School of Medicine
Los Angeles, California, 905022004, United States
San Francisco Gen Hosp
San Francisco, California, 94110, United States
UCSF / Moffitt Hosp - Pediatric
San Francisco, California, 941430105, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Savita Pahwa
- STUDY CHAIR
Howard Rosenblatt
Study Design
- Study Type
- observational
- Sponsor Type
- NIH
Study Record Dates
First Submitted
November 2, 1999
First Posted
August 31, 2001
Study Start
September 1, 1997
Last Updated
August 1, 2008
Record last verified: 2003-06