NCT00000495

Brief Summary

To determine whether improved nutrition to correct overweight and high sodium intake, and regular frequent moderate rhythmic exercise to improve cardio-pulmonary fitness and to slow heart rate could lower blood pressure and prevent development of hypertension in hypertension-prone individuals.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 1978

Completed
20.9 years until next milestone

First Submitted

Initial submission to the registry

October 27, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 28, 1999

Completed
Last Updated

November 24, 2014

Status Verified

January 1, 2000

First QC Date

October 27, 1999

Last Update Submit

November 21, 2014

Conditions

Cardiovascular DiseasesHeart DiseasesHypertensionVascular Diseases

Interventions

diet, reducingBEHAVIORAL
diet, sodium-restrictedBEHAVIORAL
alcohol restrictionBEHAVIORAL
exerciseBEHAVIORAL

Eligibility Criteria

Age30 Years - 44 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Men and women, ages 30 to 44. Normal high blood pressure of 80-89 mm Hg.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (2)

  • Stamler R, Stamler J, Gosch FC, McDonald AM. Primary prevention of hypertension--a randomized controlled trial. Ann Clin Res. 1984;16 Suppl 43:136-42.

    PMID: 6398983BACKGROUND

  • Stamler R, Stamler J, Gosch FC, Civinelli J, Fishman J, McKeever P, McDonald A, Dyer AR. Primary prevention of hypertension by nutritional-hygienic means. Final report of a randomized, controlled trial. JAMA. 1989 Oct 6;262(13):1801-7.

    PMID: 2778913BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesHeart DiseasesHypertensionVascular Diseases

Interventions

Diet, ReducingDiet, Sodium-RestrictedEthanolExercise

Intervention Hierarchy (Ancestors)

Diet TherapyNutrition TherapyTherapeuticsDietNutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological PhenomenaAlcoholsOrganic ChemicalsMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 27, 1999

First Posted

October 28, 1999

Study Start

December 1, 1978

Last Updated

November 24, 2014

Record last verified: 2000-01