NCT00000333

Brief Summary

The purpose of this study is to compare the efficacy of benztropine (or DA reuptake inhibitor) with atropine and placebo in affecting stimulated craving to cocaine cues.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started May 2001

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
1.6 years until next milestone

Study Start

First participant enrolled

May 1, 2001

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2003

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2003

Completed
Last Updated

February 24, 2017

Status Verified

December 1, 2002

Enrollment Period

1.7 years

First QC Date

September 20, 1999

Last Update Submit

February 23, 2017

Conditions

Cocaine-Related Disorders

Outcome Measures

Primary Outcomes (1)

  • Stimulated and non-stimulated craving

Interventions

BenztropineDRUG

Eligibility Criteria

Age22 Years - 48 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Washington DC VA

Washington D.C., District of Columbia, 20422, United States

Location

MeSH Terms

Conditions

Cocaine-Related Disorders

Interventions

Benztropine

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

TropanesAzabicyclo CompoundsAza CompoundsOrganic ChemicalsAlkaloidsHeterocyclic CompoundsBridged Bicyclo Compounds, HeterocyclicHeterocyclic Compounds, Bridged-Ring

Study Officials

  • Steven Deutsch, M.D.

    Washington D.C. Veterans Affairs Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 2
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Start

May 1, 2001

Primary Completion

January 1, 2003

Study Completion

April 1, 2003

Last Updated

February 24, 2017

Record last verified: 2002-12

Locations

US(1)