NCT00000332

Brief Summary

The purpose of this study is to determine if nimodipine is more effective than placebo in reducing stimulated craving for cocaine in cocaine dependent individuals denied access to cocaine in inpatient unit.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started May 1998

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 1998

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2000

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2000

Completed
Last Updated

February 24, 2017

Status Verified

December 1, 2002

Enrollment Period

1.7 years

First QC Date

September 20, 1999

Last Update Submit

February 23, 2017

Conditions

Cocaine-Related Disorders

Outcome Measures

Primary Outcomes (4)

  • Stimulated and non-stimulated craving

  • Stimulated and non-stimulated withdrawal

  • Anxiety, depression

  • Heart rate

Interventions

NimodipineDRUG

Eligibility Criteria

Age22 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Washington DC VA

Washington D.C., District of Columbia, 20422, United States

Location

MeSH Terms

Conditions

Cocaine-Related Disorders

Interventions

Nimodipine

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

DihydropyridinesPyridinesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsNicotinic Acids

Study Officials

  • Steven Deutsch, M.D.

    Washington D.C. Veterans Affairs Medical Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 2
Purpose
TREATMENT
Sponsor Type
NIH

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Start

May 1, 1998

Primary Completion

January 1, 2000

Study Completion

April 1, 2000

Last Updated

February 24, 2017

Record last verified: 2002-12

Locations

US(1)