NCT00000270

Brief Summary

The purpose of this study is to define temporal profile of brain activation (rCBF) using Xenon-SPECT and O 15-PET.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Dec 1995

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 30, 1995

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 1995

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 1995

Completed
3.7 years until next milestone

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
Last Updated

August 2, 2017

Status Verified

July 1, 2017

Enrollment Period

Same day

First QC Date

September 20, 1999

Last Update Submit

August 1, 2017

Conditions

Cocaine-Related Disorders

Keywords

cocaine

Outcome Measures

Primary Outcomes (3)

  • Absolute change in rCBF at 5 & 15 minutes (Xe)

  • Relative change in rCBF at 5, 19, & 33 minutes (O15)

  • Correlated with a) subjective effects, b) venous blood level of coca, c) autonomic variables

Interventions

CocaineDRUG

Eligibility Criteria

Age18 Years - 48 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

New York State Psychiatric Institute

New York, New York, 10032, United States

Location

Related Publications (1)

  • ACNP Abstract, 1995. CPDD Abstract, 1996. Society for Nuclear Medicine, 1996. Society for Neuroscience, 1997.

    BACKGROUND

MeSH Terms

Conditions

Cocaine-Related Disorders

Interventions

Cocaine

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

TropanesAzabicyclo CompoundsAza CompoundsOrganic ChemicalsAlkaloidsHeterocyclic CompoundsBridged Bicyclo Compounds, HeterocyclicHeterocyclic Compounds, Bridged-Ring

Study Officials

  • Herbert Kleber, M.D.

    New York State Psychiatric Institute

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 4
Purpose
TREATMENT
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Start

December 30, 1995

Primary Completion

December 30, 1995

Study Completion

December 30, 1995

Last Updated

August 2, 2017

Record last verified: 2017-07

Locations

US(1)