NCT00000214

Brief Summary

The purpose of this study is to evaluate the effects of buprenorpine on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jan 1992

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1992

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 1993

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 1993

Completed
6.7 years until next milestone

First Submitted

Initial submission to the registry

September 20, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 21, 1999

Completed
Last Updated

August 31, 2015

Status Verified

December 1, 2012

Enrollment Period

1 year

First QC Date

September 20, 1999

Last Update Submit

August 27, 2015

Conditions

Cocaine-Related Disorders

Keywords

intravenous abuse

Outcome Measures

Primary Outcomes (4)

  • Direct cocaine effects (caridio, subjective)

  • Interaction of coc/bup on cardio measures

  • Ineraction of coc/bup on coc's subjective effects

  • Effects of buprenorphine on cocaine craving

Interventions

BuprenorphineDRUG

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Please contact site for information.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Columbia University

New York, New York, 10023, United States

Location

Related Publications (1)

  • Behav Pharm 1994, vol 5: 79-89

    BACKGROUND

MeSH Terms

Conditions

Cocaine-Related Disorders

Interventions

Buprenorphine

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

MorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic Compounds

Study Officials

  • Richard Foltin, Ph.D.

    Columbia University

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
phase 2
Purpose
TREATMENT
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 20, 1999

First Posted

September 21, 1999

Study Start

January 1, 1992

Primary Completion

January 1, 1993

Study Completion

January 1, 1993

Last Updated

August 31, 2015

Record last verified: 2012-12

Locations

US(1)