Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

3.6%

1 terminated/withdrawn out of 28 trials

Success Rate

96.0%

+9.5% vs industry average

Late-Stage Pipeline

36%

10 trials in Phase 3/4

Results Transparency

50%

12 of 24 completed trials have results

Key Signals

12 with results

Enrollment Performance

Analytics

Phase 2
12(42.9%)
Phase 1
6(21.4%)
Phase 3
6(21.4%)
Phase 4
4(14.3%)
28Total
Phase 2(12)
Phase 1(6)
Phase 3(6)
Phase 4(4)

Activity Timeline

Global Presence

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Clinical Trials (28)

Showing 20 of 28 trials
NCT02173301Phase 2Completed

A Study to Assess the Efficacy and Safety of XP23829 in Subjects With Moderate-to-Severe Chronic Plaque-Type Psoriasis

Role: collaborator

NCT02560766Phase 4Unknown

An Efficacy and Safety Evaluation of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS

Role: lead

NCT02633683Phase 4Unknown

An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS

Role: lead

NCT01668667Phase 4Completed

Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment Study

Role: lead

NCT00914602Phase 1Completed

An Exploratory Study of XP21279 (With Lodosyn®) and Sinemet® in Parkinson's Disease Subjects

Role: lead

NCT02633657Phase 1Withdrawn

A PK and Safety Evaluation of HORIZANT (Gabapentin Enacarbil) in Adolescents With Moderate-to-Severe Primary RLS

Role: lead

NCT01516372Phase 1Completed

A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers

Role: lead

NCT00557401Phase 2Completed

An Efficacy and Safety Study of XP19986 in Subjects With Symptomatic GERD

Role: lead

NCT01359566Phase 3Completed

Efficacy and Safety of Arbaclofen Placarbil in Subjects With Spasticity Due to Multiple Sclerosis

Role: lead

NCT00978016Phase 2Completed

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Role: lead

NCT00817986Phase 2Completed

A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms

Role: lead

NCT00557973Phase 2Completed

A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury

Role: lead

NCT01171313Phase 2Completed

A Efficacy, Safety and Pharmacokinetic Study of XP21279 and Sinemet® in Parkinson's Disease Subjects

Role: lead

NCT02424695Phase 4Unknown

Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome

Role: collaborator

NCT01332318Phase 2Completed

Simulated Driving Study in Restless Legs Syndrome

Role: lead

NCT00619476Phase 2Completed

A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN)

Role: lead

NCT00333359Phase 3Completed

XP13512 (Gabapentin Enacarbil) Extension Study in Patients With Restless Legs Syndrome.

Role: lead

NCT00643760Phase 2Completed

A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)

Role: lead

NCT01332305Phase 2Completed

Dose-Response and Pharmacokinetics of Gabapentin Enacarbil (GEn [XP13512 / GSK1838262]) in Restless Legs Syndrome

Role: lead

NCT00365352Phase 3Completed

XP13512 vs. Placebo in Patients With Restless Legs Syndrome.

Role: lead