Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

30.4%

7 terminated/withdrawn out of 23 trials

Success Rate

63.2%

-23.3% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

6 of 12 completed trials have results

Key Signals

6 with results7 terminated

Enrollment Performance

Analytics

Phase 1
15(65.2%)
Phase 2
7(30.4%)
N/A
1(4.3%)
23Total
Phase 1(15)
Phase 2(7)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT03260023Phase 1Active Not Recruiting

Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

Role: lead

NCT04183166Phase 1Active Not Recruiting

A Clinical Trial Evaluating TG4050 in Head and Neck Cancer

Role: lead

NCT04725331Phase 1Terminated

A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors

Role: lead

NCT03839524Phase 1Completed

A Trial Evaluating TG4050 in Ovarian Carcinoma.

Role: lead

NCT02823990Phase 2Completed

TG4010 and Nivolumab in Patients With Lung Cancer

Role: collaborator

NCT05788926Phase 1Terminated

A Clinical Trial of TG6050 in Patients With Metastatic Non-Small Cell Lung Cancer (Delivir)

Role: lead

NCT04194034Phase 1Terminated

Study of Intrahepatic Arterial Infusion of TG6002 in Combination With 5-FC in Patients With Metastatic Colorectal Cancer

Role: lead

NCT03724071Phase 1Terminated

Study of TG6002 (VV TK-RR-FCU1) in Combination With 5-FC in Patients With Advanced Gastro-intestinal Tumors.

Role: lead

NCT02977156Phase 1Completed

Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors.

Role: collaborator

NCT02630368Phase 1Unknown

A Study of Metronomic CP and JX-594 in Patients With Advanced Breast Cancer and Advanced Soft-tissue Sarcoma (METROmaJX)

Role: collaborator

NCT03353675Phase 2Completed

A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC)

Role: lead

NCT03071094Phase 1Terminated

A Trial to Evaluate the Safety and Efficacy of the Combination of the Oncolytic Immunotherapy Pexa-Vec With the PD-1 Receptor Blocking Antibody Nivolumab in the First-line Treatment of Advanced Hepatocellular Carcinoma (HCC)

Role: lead

NCT01394939Phase 1Completed

Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

Role: collaborator

NCT02428400Phase 1Completed

Safety and Tolerability of TG1050: A Dose-finding Study

Role: lead

NCT03294486Phase 1Unknown

Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients

Role: collaborator

NCT01383148Phase 2Terminated

Phase IIB/III Of TG4010 Immunotherapy In Patients With Stage IV Non-Small Cell Lung Cancer

Role: lead

NCT02355951Not ApplicableCompleted

Non-investigational Study to Evaluate Adenovirus Serotype 5 (Ad5) Neutralizing Antibodies (nAb) in Patients With Chronic Hepatitis B Virus (HBV) Mono-infection

Role: lead

NCT00415818Phase 2Completed

Immunotherapy With TG4010 in Patients With Advanced Non-Small Cell Lung Cancer

Role: lead

NCT00394693Phase 2Completed

Study to Evaluate the Safety and Efficacy of Adeno-IFN Gamma in Cutaneous B-cell Lymphoma

Role: lead

NCT00978107Phase 1Completed

Trial of TG4023 Combined With Flucytosine in Liver Tumors

Role: lead