Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 5/100

Failure Rate

8.7%

2 terminated/withdrawn out of 23 trials

Success Rate

90.0%

+3.4% vs industry average

Late-Stage Pipeline

48%

11 trials in Phase 3/4

Results Transparency

94%

17 of 18 completed trials have results

Key Signals

2 recruiting17 with results

Enrollment Performance

Analytics

Phase 2
11(50.0%)
Phase 3
8(36.4%)
Phase 4
3(13.6%)
22Total
Phase 2(11)
Phase 3(8)
Phase 4(3)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT07028749Phase 2Recruiting

Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

Role: collaborator

NCT07521007Phase 2Recruiting

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

Role: collaborator

NCT04363697Phase 4Completed

Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

Role: lead

NCT03705234Phase 3Active Not Recruiting

A Randomized Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Cardiovascular Disease

Role: collaborator

NCT05492500Phase 2Terminated

A Study of Ponsegromab in People With Heart Failure

Role: collaborator

NCT04610892Phase 2Completed

Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction

Role: collaborator

NCT04128475Terminated

Observational Study of Cardiovascular Disease.

Role: collaborator

NCT04409834Phase 4Completed

Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial

Role: lead

NCT01380730Phase 2Completed

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy

Role: collaborator

NCT04516291Phase 2Completed

A Dose-Ranging Study With Vupanorsen (TRANSLATE-TIMI 70)

Role: collaborator

NCT03578809Phase 2Completed

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction

Role: collaborator

NCT01730534Phase 3Completed

Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events

Role: collaborator

NCT01235351Phase 2Completed

Escalating Clopidogrel by Involving a Genetic Strategy - Thrombolysis In Myocardial Infarction 56

Role: lead

NCT02019264Phase 4Completed

A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors

Role: collaborator

NCT00781391Phase 3Completed

Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation

Role: collaborator

NCT00617123Phase 3Completed

Trial to Assess the Ocular Safety of Vorapaxar (SCH 530348) in Participants With Atherosclerosis (Study P05183)

Role: collaborator

NCT00526474Phase 3Completed

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737)

Role: collaborator

NCT01000727Phase 3Completed

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial

Role: collaborator

NCT02145468Phase 3Completed

A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)

Role: collaborator

NCT00409578Phase 2Completed

Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome

Role: collaborator