Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.0%

2 terminated/withdrawn out of 25 trials

Success Rate

92.0%

+5.5% vs industry average

Late-Stage Pipeline

12%

3 trials in Phase 3/4

Results Transparency

74%

17 of 23 completed trials have results

Key Signals

17 with results

Enrollment Performance

Analytics

Phase 1
14(56.0%)
Phase 2
5(20.0%)
N/A
3(12.0%)
Phase 3
2(8.0%)
Phase 4
1(4.0%)
25Total
Phase 1(14)
Phase 2(5)
N/A(3)
Phase 3(2)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (25)

Showing 20 of 25 trials
NCT02251704Phase 4Completed

Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan Africa

Role: collaborator

NCT03813108Not ApplicableTerminated

Safety and Efficacy of NF135 CPS Immunization

Role: collaborator

NCT04238689Phase 1Completed

Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31F

Role: collaborator

NCT03138096Phase 1Completed

Safety and Protective Efficacy of Pb(PfCS@UIS4)

Role: collaborator

NCT00223990Phase 2Completed

Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine

Role: collaborator

NCT03162614Phase 2Completed

Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Role: collaborator

NCT01190202Not ApplicableCompleted

Epidemiology Study of Malaria Transmission Intensity in Africa

Role: collaborator

NCT03454048Not ApplicableCompleted

Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2

Role: collaborator

NCT00866619Phase 3Completed

Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa

Role: collaborator

NCT01857869Phase 2Completed

Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Role: collaborator

NCT01366534Phase 2Completed

Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve Adults

Role: collaborator

NCT01157897Phase 1Completed

Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults

Role: collaborator

NCT00312663Phase 1Completed

Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America

Role: collaborator

NCT00312702Phase 1Completed

Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America

Role: collaborator

NCT01323972Phase 3Completed

Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in Children

Role: collaborator

NCT01231503Phase 2Completed

Safety and Immunogenicity of GSK Biologicals' Malaria Vaccine 257049 When Administered on 7 Schedules to African Infants

Role: collaborator

NCT02836002Phase 1Completed

Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1

Role: collaborator

NCT00317473Phase 1Completed

Phase 1 Trial of a Malaria Vaccine in Young Kenyan Children

Role: collaborator

NCT02252640Phase 1Completed

A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S

Role: collaborator

NCT00385047Phase 1Completed

A Study to Determine Whether 2 Investigational Malaria Vaccines Are Safe, Protective Against Malaria in Adults

Role: collaborator