Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

10.3%

7 terminated/withdrawn out of 68 trials

Success Rate

87.0%

+0.5% vs industry average

Late-Stage Pipeline

31%

21 trials in Phase 3/4

Results Transparency

28%

13 of 47 completed trials have results

Key Signals

4 recruiting13 with results7 terminated

Enrollment Performance

Analytics

Phase 2
25(36.8%)
Phase 1
22(32.4%)
Phase 3
21(30.9%)
68Total
Phase 2(25)
Phase 1(22)
Phase 3(21)

Activity Timeline

Global Presence

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Clinical Trials (68)

Showing 20 of 68 trials
NCT04104139Phase 1Active Not Recruiting

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

Role: collaborator

NCT04920032Phase 1Recruiting

Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

Role: collaborator

NCT05568095Phase 3Active Not Recruiting

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Role: collaborator

NCT06608927Phase 3Active Not Recruiting

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Role: collaborator

NCT04683250Phase 1Recruiting

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

Role: lead

NCT05245968Phase 1Active Not Recruiting

A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101)

Role: lead

NCT04608110Phase 1Recruiting

A Phase 1 Trial of ASTX030 in Patients With Myelodysplastic Syndrome

Role: lead

NCT04587908Phase 3Active Not Recruiting

A Phase 3 Study of TAS-205 in Patients With Duchenne Muscular Dystrophy(REACH-DMD)

Role: lead

NCT05773092Phase 2Active Not Recruiting

A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC

Role: collaborator

NCT04923529Phase 2Completed

TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma

Role: collaborator

NCT03175029Phase 2Completed

Exploratory Study of TAC-302 in Detrusor Underactivity Patients With Overactive Bladder.

Role: lead

NCT02261532Phase 1Completed

A Phase I Study of TAS-102 in Solid Tumors

Role: lead

NCT02906683Phase 2Completed

Exploratory Trial of TAS-303 in Female Patients With Stress Urinary Incontinence

Role: lead

NCT04999761Phase 1Recruiting

AB122 Platform Study

Role: lead

NCT01904253Phase 2Terminated

A Phase 2 Study Comparing TAS-102 Versus Topotecan or Amrubicin to Treat Small Cell Lung Cancer Following Platinum-Based Chemotherapy

Role: collaborator

NCT05691660Phase 1Completed

A Study of TAS3731 in Healthy Adults

Role: lead

NCT05335499Phase 2Completed

A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria

Role: lead

NCT04074343Phase 1Completed

TAS-102 and Irinotecan in 2L+ Gastric and Gastroesophageal Adenocarcinoma

Role: collaborator

NCT05621447Phase 1Completed

A Mass Balance Study of [14C] TAS-303 in Healthy Adult Male Subjects

Role: lead

NCT02943733Phase 1Terminated

Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs

Role: collaborator