Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

15.8%

6 terminated/withdrawn out of 38 trials

Success Rate

82.9%

-3.6% vs industry average

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

31%

9 of 29 completed trials have results

Key Signals

9 with results6 terminated

Enrollment Performance

Analytics

Phase 1
21(55.3%)
Phase 2
15(39.5%)
Phase 3
2(5.3%)
38Total
Phase 1(21)
Phase 2(15)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (38)

Showing 20 of 38 trials
NCT01167114Phase 2Completed

STA-9090 in Previously Treated Patients With Advanced Esophagogastric Cancer

Role: collaborator

NCT02008877Phase 1Completed

SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

Role: collaborator

NCT01173523Phase 2Completed

Study of Hsp90 Inhibitor, STA-9090 for Relapsed or Refractory Small Cell Lung Cancer

Role: collaborator

NCT01200238Phase 2Completed

STA-9090(Ganetespib) in Metastatic Ocular Melanoma

Role: collaborator

NCT02060253Phase 1Completed

Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer

Role: collaborator

NCT01665937Phase 1Completed

STA-9090 in Patients With Advanced Hepatocellular Cancer

Role: collaborator

NCT02261805Phase 1Terminated

A Phase I/II Study of Ganetespib in Combination With Doxorubicin

Role: collaborator

NCT01551693Phase 2Terminated

STA-9090(Ganetespib) in Patients With Unresectable Stage III or Stage IV Melanoma

Role: collaborator

NCT02334319Phase 1Terminated

Ganetespib Window of Opportunity Study in Head and Neck Cancers

Role: collaborator

NCT01798485Phase 3Terminated

A Phase 3 Study of Ganetespib in Combination With Docetaxel Versus Docetaxel Alone in Patients With Advanced NSCLC

Role: lead

NCT01039519Phase 2Completed

A Study Evaluating STA-9090 in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor (GIST)

Role: lead

NCT01554969Phase 1Completed

Phase I Trial of Ganetespib, Capecitabine, and Radiation in Rectal Cancer

Role: collaborator

NCT01111838Phase 2Completed

Clinical and Translational Study of STA-9090

Role: collaborator

NCT01273896Phase 2Completed

Open-label Study of STA-9090 for Patients With Metastatic Breast Cancer

Role: collaborator

NCT01677455Phase 2Completed

An Open-Label Multicenter Phase 2 Window of Opportunity Study Evaluating Ganetespib in Women With Breast Cancer

Role: lead

NCT01348126Phase 2Terminated

Study of Ganetespib (STA-9090) + Docetaxel in Advanced Non Small Cell Lung Cancer

Role: lead

NCT01485835Phase 1Completed

A Phase I Study of Ganetespib +/- Bortezomib in Patients With Relapsed and/or Refractory Multiple Myeloma

Role: collaborator

NCT01562015Phase 2Completed

A Study of Ganetespib in Subjects With ALK-Positive Non-Small-Cell Lung Cancer (NSCLC)

Role: lead

NCT01031225Phase 2Completed

A Study of the HSP90 Inhibitor, STA-9090 in Subjects With Stage IIIB or IV Non-Small Cell Lung Cancer (NSCLC)

Role: lead

NCT01183364Phase 1Completed

A Dose Escalation Study of STA-9090 and Docetaxel in Patients With Solid Tumors

Role: lead