Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

35.7%

5 terminated/withdrawn out of 14 trials

Success Rate

61.5%

-25.0% vs industry average

Late-Stage Pipeline

29%

4 trials in Phase 3/4

Results Transparency

25%

2 of 8 completed trials have results

Key Signals

2 with results

Enrollment Performance

Analytics

Phase 2
6(50.0%)
Phase 3
4(33.3%)
Phase 1
2(16.7%)
12Total
Phase 2(6)
Phase 3(4)
Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT01172509Phase 1Terminated

TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers

Role: collaborator

NCT01706523Phase 3Terminated

Open Label Extension Study of STX209 (Arbaclofen) in Autism Spectrum Disorders

Role: lead

NCT01282268Phase 3Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for Social Withdrawal in Adolescents and Adults With Fragile X Syndrome

Role: lead

NCT01325220Phase 3Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome

Role: lead

NCT01555333Phase 3Terminated

An Open Label Extension Study in Subjects With Fragile X Syndrome

Role: lead

NCT01288716Phase 2Completed

Study of Arbaclofen for the Treatment of Social Withdrawal in Subjects With Autism Spectrum Disorders

Role: lead

NCT00892580Completed

Biomarker and DNA Collection in Subjects Participating in Protocol 22003

Role: lead

NCT00823368Completed

Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001

Role: lead

NCT00846547Phase 2Completed

Open-Label Study of the Safety and Tolerability of STX209 in Subjects With Autism Spectrum Disorders

Role: lead

NCT00788073Phase 2Completed

Safety, Tolerability and Efficacy Study of STX209 in Subjects With Fragile X Syndrome

Role: lead

NCT01064973Phase 2Terminated

An Open Label Extension Study of STX209 in Subjects With Autism Spectrum Disorders

Role: lead

NCT01325740Phase 2Suspended

A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome

Role: lead

NCT01013480Phase 2Terminated

An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome

Role: lead

NCT00965432Phase 1Completed

A Single-Dose Study in Normal Volunteers to Assess the Safety, Tolerability and Pharmacokinetics of STX107

Role: lead

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