Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 85/100

Failure Rate

17.6%

3 terminated/withdrawn out of 17 trials

Success Rate

0.0%

-86.5% vs industry average

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

0%

0 of 0 completed trials have results

Key Signals

7 recruiting

Enrollment Performance

Analytics

Phase 2
9(60.0%)
Phase 1
4(26.7%)
Phase 3
1(6.7%)
Early Phase 1
1(6.7%)
15Total
Phase 2(9)
Phase 1(4)
Phase 3(1)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT06623110Phase 2Recruiting

Phase II Study of RP2 as Immunoprevention in High-Risk Oral Precancerous Disease

Role: collaborator

NCT04349436Phase 1Active Not Recruiting

Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies

Role: lead

NCT06216938Early Phase 1Recruiting

RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis

Role: collaborator

NCT06581406Phase 2Recruiting

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Role: lead

NCT05733598Phase 2Recruiting

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

Role: lead

NCT06898970Phase 2Recruiting

Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for Angiosarcoma

Role: collaborator

NCT06264180Phase 3Recruiting

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

Role: lead

NCT04336241Phase 1Active Not Recruiting

Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors

Role: lead

NCT04735978Phase 1Active Not Recruiting

Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours

Role: lead

NCT03767348Phase 2Active Not Recruiting

Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)

Role: lead

NCT05733611Phase 2Terminated

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

Role: lead

NCT06887348Recruiting

A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

Role: lead

NCT07059611Phase 2Not Yet Recruiting

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

Role: collaborator

NCT06590480Unknown

An Expanded Access Program for VO (RP1) in Combination With Nivolumab in Patients With Advanced Melanoma

Role: lead

NCT06067061Phase 1Terminated

"neoBREASTIM": Atezolizumab Plus RP1 Oncolytic Immunotherapy in the NeoAdjuvant Setting of Triple-Negative Breast Cancer

Role: collaborator

NCT05743270Phase 2Withdrawn

Study of RP3 in Combination With Nivolumab and Other Therapy in Patients With Locoregionally Advanced or Recurrent SCCHN

Role: lead

NCT04050436Phase 2Active Not Recruiting

Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer

Role: lead

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