Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

12.5%

11 terminated/withdrawn out of 88 trials

Success Rate

83.8%

-2.7% vs industry average

Late-Stage Pipeline

30%

26 trials in Phase 3/4

Results Transparency

28%

16 of 57 completed trials have results

Key Signals

9 recruiting16 with results7 terminated4 withdrawn

Enrollment Performance

Analytics

Phase 2
23(31.1%)
Phase 3
22(29.7%)
Phase 1
20(27.0%)
N/A
5(6.8%)
Phase 4
4(5.4%)
74Total
Phase 2(23)
Phase 3(22)
Phase 1(20)
N/A(5)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (88)

Showing 20 of 88 trials
NCT05195632Phase 2Active Not Recruiting

Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer

Role: lead

NCT05004350Phase 2Completed

A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.

Role: lead

NCT04913285Phase 1Active Not Recruiting

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

Role: lead

NCT04554914Phase 2Active Not Recruiting

A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases

Role: lead

NCT06043817Phase 1Recruiting

First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

Role: lead

NCT04074096Phase 2Active Not Recruiting

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis

Role: collaborator

NCT03394365Phase 3Recruiting

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Role: lead

NCT06690489Completed

An Observational Real-world Study to Evaluate the Impact of Dermatological Toxicities on the Quality of Life in Patients With Early Breast Cancer Treated With Adjuvant Endocrine Therapy - BCARE (Breast Cancer Adjuvant Real-world Evaluation of Dermatological Adverse Events)

Role: lead

NCT04911998Completed

A Prospective Observational Study on Targeted Therapy for Unresectable or Metastatic BRAFV600E Mutant Melanoma Patients

Role: lead

NCT04317599Completed

A Retrospective Non Interventional Study on First Line Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)

Role: lead

NCT06688370Terminated

The Performance and Safety of Petit Drill in the French Paediatric Population: a Post-market Clinical Follow-up Study

Role: lead

NCT05639413Not ApplicableRecruiting

A Clinical-biological Prospective Cohort of Patients With BRAFV600E-mutated Metastatic Colorectal Cancer

Role: collaborator

NCT05599334Completed

A Retrospective Observational Study of Patients With Early-stage HER2-positive Breast Cancer, Treated With Neratinib

Role: lead

NCT06567015Phase 1Recruiting

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

Role: lead

NCT07144709Completed

A 6-months Observational Study to Evaluate the Quality of Life of Patients Treated With Phytotherapy or Alpha-blockers for Benign Prostatic Hyperplasia

Role: lead

NCT07096206Active Not Recruiting

Characteristics and Impacts of X-linked Hypohidrotic Ectodermal Dysplasia (XLHED) in Boys: An Observational International Study

Role: lead

NCT06500494Recruiting

To Describe How Well Vinorelbine Given Orally Works in Patients With a Breast Cancer After 2 Years of Treatment

Role: lead

NCT05546905Completed

A Study in Patients With BRAF V600E-mutant Metastatic Non-small Cell Lung Cancer (OCTOPUS)

Role: lead

NCT06669117Phase 1Recruiting

FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations

Role: lead

NCT06623773Completed

Study on Structum® in Adult Patients With Osteoarthritis (TRUST)

Role: lead