Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 85/100

Failure Rate

22.9%

11 terminated/withdrawn out of 48 trials

Success Rate

57.7%

-28.8% vs industry average

Late-Stage Pipeline

6%

3 trials in Phase 3/4

Results Transparency

0%

0 of 15 completed trials have results

Key Signals

8 recruiting9 terminated

Enrollment Performance

Analytics

Phase 1
29(60.4%)
Phase 2
16(33.3%)
Phase 3
3(6.3%)
48Total
Phase 1(29)
Phase 2(16)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (48)

Showing 20 of 48 trials
NCT07566897Phase 1Not Yet Recruiting

A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With Ruxolitinib in Patients With Advanced Solid Tumors

Role: lead

NCT06336291Phase 2Active Not Recruiting

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence

Role: lead

NCT07227350Phase 2Not Yet Recruiting

L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)

Role: lead

NCT07228442Phase 2Not Yet Recruiting

L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

Role: lead

NCT07227870Phase 2Not Yet Recruiting

L19IL2/TNF in Patients With Basal Cell Carcinoma

Role: lead

NCT04471987Phase 1Recruiting

Safety and Early Signs of Efficacy of IL12-L19L19.

Role: lead

NCT06640413Phase 1Recruiting

A Study to Evaluate the Safety and Preliminary Signs of Efficacy of [177Lu]Lu-OncoFAP-23 Alone or in Combination With L19-IL2 as a Treatment of Metastatic FAP-positive Solid Tumors

Role: lead

NCT06840548Phase 1Completed

A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer

Role: lead

NCT07245992Phase 1Recruiting

A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis

Role: lead

NCT06840535Phase 1Completed

A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoACP3 in Patients With Prostate Cancer

Role: lead

NCT03567889Phase 3Recruiting

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

Role: lead

NCT05622175Phase 1Withdrawn

Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment

Role: lead

NCT07120984Phase 2Not Yet Recruiting

A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or Oligodendroglioma

Role: lead

NCT04733183Phase 2Active Not Recruiting

Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma

Role: lead

NCT05784597Phase 1Completed

A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors

Role: lead

NCT06284590Phase 2Recruiting

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients

Role: lead

NCT02938299Phase 3Active Not Recruiting

Neoadjuvant L19IL2/L19TNF- Pivotal Study

Role: lead

NCT04573192Phase 1Recruiting

A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression

Role: lead

NCT04032964Phase 1Active Not Recruiting

Dose Finding Study of L19TNF and Doxorubicin in Patients With STS

Role: lead

NCT05304663Phase 1Withdrawn

Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression

Role: lead