Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

72.7%

8 terminated/withdrawn out of 11 trials

Success Rate

20.0%

-66.5% vs industry average

Late-Stage Pipeline

73%

8 trials in Phase 3/4

Results Transparency

0%

0 of 2 completed trials have results

Key Signals

8 terminated

Enrollment Performance

Analytics

Phase 3
8(72.7%)
Phase 2
3(27.3%)
11Total
Phase 3(8)
Phase 2(3)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT01089790Phase 3Terminated

Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone

Role: collaborator

NCT00947557Phase 3Terminated

Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Glimepiride With or Without Metformin

Role: collaborator

NCT00970424Phase 3Terminated

Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Pioglitazone

Role: collaborator

NCT00850239Phase 3Terminated

Safety and Efficacy Study of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Role: lead

NCT00865592Phase 3Terminated

Long-term Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus

Role: lead

NCT01101945Phase 2Terminated

Long-term Extension Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus

Role: lead

NCT00998686Phase 3Terminated

Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Role: lead

NCT00690638Phase 3Completed

Safety and Efficacy Study of Dutogliptin/PHX1149T to Treat Type 2 Diabetes Mellitus

Role: lead

NCT00958269Phase 3Terminated

Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment

Role: lead

NCT00482950Phase 2Unknown

A Study to Evaluate Safety and Efficacy of PHX1149T in Subjects With Type 2 Diabetes Mellitus

Role: lead

NCT00530881Phase 2Completed

Randomized, Double-Blind, Placebo-Controlled, With PHX1149 in Patients With Type 2 Diabetes Mellitus

Role: lead

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