Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

16.7%

2 terminated/withdrawn out of 12 trials

Success Rate

71.4%

-15.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

120%

6 of 5 completed trials have results

Key Signals

2 recruiting6 with results

Enrollment Performance

Analytics

Phase 1
9(75.0%)
Phase 2
3(25.0%)
12Total
Phase 1(9)
Phase 2(3)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT04784247Phase 2Active Not Recruiting

Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma

Role: collaborator

NCT05478837Phase 1Active Not Recruiting

Genetically Modified Cells (KIND T Cells) for the Treatment of HLA-A*0201-Positive Patients With H3.3K27M-Mutated Glioma

Role: collaborator

NCT04196413Phase 1Recruiting

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)

Role: collaborator

NCT05474378Phase 1Recruiting

B7-H3 Chimeric Antigen Receptor T Cells (B7-H3CART) in Recurrent Glioblastoma Multiforme

Role: collaborator

NCT04007029Phase 1Active Not Recruiting

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Role: collaborator

NCT03817125Phase 1Completed

Melanoma Checkpoint and Gut Microbiome Alteration With Microbiome Intervention

Role: lead

NCT03730948Phase 1Terminated

DC Vaccine in Colorectal Cancer

Role: collaborator

NCT03835533Phase 1Completed

Platform Study for Prostate Researching Translational Endpoints Correlated to Response to Inform Use of Novel Combinations

Role: lead

NCT03651271Phase 2Completed

Nivolumab With or Without Ipilimumab in Advanced Metastatic Cancer

Role: lead

NCT03399448Phase 1Terminated

NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)

Role: collaborator

NCT03214250Phase 1Completed

Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

Role: lead

NCT02731729Phase 2Completed

Ipilimumab vs Ipilimumab Plus Nivolumab in Patients With Stage III-IV Melanoma Who Have Progressed or Relapsed on PD-1 Inhibitor Therapy

Role: lead

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