Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

24.7%

18 terminated/withdrawn out of 73 trials

Success Rate

75.3%

-11.2% vs industry average

Late-Stage Pipeline

7%

5 trials in Phase 3/4

Results Transparency

75%

41 of 55 completed trials have results

Key Signals

41 with results14 terminated4 withdrawn

Enrollment Performance

Analytics

Phase 2
53(72.6%)
Phase 1
14(19.2%)
Phase 3
4(5.5%)
Phase 4
1(1.4%)
Early Phase 1
1(1.4%)
73Total
Phase 2(53)
Phase 1(14)
Phase 3(4)
Phase 4(1)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (73)

Showing 20 of 73 trials
NCT00640978Phase 2Terminated

Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer

Role: collaborator

NCT00942734Phase 2Completed

Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma

Role: collaborator

NCT01032070Phase 2Terminated

Erlotinib Versus Oral Etoposide in Patients With Recurrent or Refractory Pediatric Ependymoma

Role: lead

NCT01247922Phase 2Terminated

Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205

Role: lead

NCT01010945Phase 1Completed

Erlotinib, Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer

Role: lead

NCT01174043Phase 2Completed

Pilot Study of Erlotinib for the Treatment of Patients With de Novo Acute Myeloid Leukemia

Role: collaborator

NCT01257594Phase 1Completed

EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas

Role: collaborator

NCT01515137Phase 1Completed

Study of TARCEVA (Erlotinib) as Adjuvant Treatment for Locally Advanced Head and Neck Squamous Cell Carcinoma

Role: collaborator

NCT01180959Phase 2Completed

Erlotinib Plus Bevacizumab in Hepatocellular Carcinoma (HCC) as Second-line Therapy

Role: collaborator

NCT00553800Phase 2Completed

Study of Bevacizumab and Erlotinib in Patients With Advanced Non-small Cell Lung Cancer

Role: collaborator

NCT01154335Phase 1Completed

Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal Cancer

Role: collaborator

NCT00591123Phase 2Completed

Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia

Role: collaborator

NCT00871923Phase 2Completed

Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung Cancer

Role: collaborator

NCT00570258Phase 2Terminated

Randomized, Double Blind Multicenter Phase II Study of Time to Progression on Fulvestrant in Combination With Erlotinib or Placebo in Hormone Receptor-Positive Metastatic Breast Cancer (MBC) Subjects Who Progressed on First Line Hormonal Therapy

Role: collaborator

NCT00950365Phase 2Completed

Pemetrexed Disodium With or Without Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV or Recurrent Non-Small Cell Lung Cancer

Role: collaborator

NCT01038856Phase 2Terminated

Trial of Erlotinib in Patients With JAK-2 V617F Positive Polycythemia Vera

Role: collaborator

NCT00733746Phase 2Completed

Gemcitabine and Erlotinib Before and After Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Role: collaborator

NCT00497224Phase 2Completed

Phase II Trial of Erlotinib in Advanced Pancreatic Cancer

Role: collaborator

NCT00940316Phase 2Completed

Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer

Role: collaborator

NCT00254410Phase 2Completed

FCM-R (Fludarabine, Cyclophosphamide, Mitoxantrone, Rituximab) in Previously Untreated Patients With Chronic Lymphocytic Leukemia (CLL) < 70 Years

Role: collaborator