Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 85/100

Failure Rate

18.2%

2 terminated/withdrawn out of 11 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

0%

0 of 2 completed trials have results

Key Signals

Enrollment Performance

Analytics

Phase 2
5(45.5%)
Phase 1
5(45.5%)
Phase 3
1(9.1%)
11Total
Phase 2(5)
Phase 1(5)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT00383487Phase 2Terminated

A Phase II Trial of Calcitriol and Naproxen in Patients With Recurrent Prostate Cancer

Role: collaborator

NCT00055263Phase 1Completed

A New Formulation of Calcitriol (DN-101) in Patients With Advanced Malignancies

Role: lead

NCT00043576Phase 2Unknown

ASCENT: Androgen Independent Prostate Cancer Study of Calcitriol Enhancing Taxotere

Role: lead

NCT00536770Phase 2Suspended

A Study of Gemcitabine ± Erlotinib and DN-101 Versus Gemcitabine ± Erlotinib and Placebo in Patients With Advanced Pancreatic Cancer

Role: lead

NCT00273338Phase 3Terminated

DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (AIPC Study of Calcitriol Enhancing Taxotere [ASCENT-2])

Role: lead

NCT00394628Phase 1Unknown

AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme

Role: lead

NCT00066885Phase 1Completed

Study of DN101 and Taxotere in Patients With Advanced Non-Small Cell Lung Cancer

Role: lead

NCT00109356Phase 1Unknown

Study of AQ4N in Patients With Non Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, or Small Lymphocytic Leukemia

Role: lead

NCT00090727Phase 1Unknown

Chemotherapy for Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Role: lead

NCT00057031Phase 2Unknown

Study of High-Dose Pulse Administration DN-101 (Calcitriol) in Patients With Myelodysplastic Syndrome (MDS)

Role: lead

NCT00285675Phase 2Unknown

Study of DN-101 (Calcitriol) and Docetaxel in Subjects Previously Enrolled in Studies DN101-002 or DN101-004

Role: lead

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