Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

0.0%

0 terminated/withdrawn out of 20 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

30%

6 trials in Phase 3/4

Results Transparency

62%

8 of 13 completed trials have results

Key Signals

4 recruiting8 with results

Enrollment Performance

Analytics

Phase 2
7(35.0%)
Phase 1
6(30.0%)
Phase 3
6(30.0%)
N/A
1(5.0%)
20Total
Phase 2(7)
Phase 1(6)
Phase 3(6)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (20)

Showing 20 of 20 trials
NCT06305559Phase 3Active Not Recruiting

A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque

Role: lead

NCT06496243Phase 2Recruiting

Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels

Role: lead

NCT07478887Not ApplicableRecruiting

Impact of the Corrie Lipids Digital Health Program on Lipid Optimization

Role: collaborator

NCT07219602Phase 3Recruiting

A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome

Role: lead

NCT06982508Phase 2Recruiting

Evaluation of Obicetrapib on Antioxidant Levels in Plasma and HDL Particles of Healthy Volunteers

Role: lead

NCT06005597Phase 3Completed

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Role: lead

NCT05142722Phase 3Completed

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Role: lead

NCT05425745Phase 3Completed

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.

Role: lead

NCT06081166Phase 1Completed

A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin

Role: lead

NCT05161715Phase 2Completed

Proof-of-concept, Open-label Study in Patients With Early Alzheimer's Disease

Role: lead

NCT06547359Phase 1Completed

A Study to Evaluate Drug-Drug Interactions of Obicetrapib Tablets and Ezetimibe Tablets in Healthy Adult Subjects

Role: lead

NCT05421078Phase 2Completed

A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.

Role: lead

NCT05972278Phase 1Active Not Recruiting

Investigating the Effect of Obicetrapib on Lipoprotein Metabolism

Role: lead

NCT06048302Phase 1Completed

PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function

Role: lead

NCT06250205Phase 1Completed

Evaluate the Pharmacokinetics of a Combined Oral Contraceptive (COC) With and Without Obicetrapib

Role: lead

NCT04753606Phase 2Completed

Randomized Study of Obicetrapib as an Adjunct to Statin Therapy

Role: lead

NCT05266586Phase 2Completed

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy

Role: lead

NCT06050291Phase 1Completed

Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe

Role: lead

NCT05202509Phase 3Active Not Recruiting

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

Role: lead

NCT04770389Phase 2Completed

Randomized Study of Obicetrapib in Combination With Ezetimibe

Role: lead

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