Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

38.1%

8 terminated/withdrawn out of 21 trials

Success Rate

61.9%

-24.6% vs industry average

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

85%

11 of 13 completed trials have results

Key Signals

11 with results7 terminated

Enrollment Performance

Analytics

Phase 1
10(47.6%)
Phase 2
10(47.6%)
Phase 3
1(4.8%)
21Total
Phase 1(10)
Phase 2(10)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT01761240Phase 1Completed

Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC

Role: lead

NCT00849667Phase 3Terminated

Efficacy and Safety of Farletuzumab (MORAb-003) in Combination With Carboplatin and Taxane in Participants With Platinum-sensitive Ovarian Cancer in First Relapse

Role: lead

NCT00738582Phase 2Completed

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma

Role: lead

NCT01507545Phase 2Terminated

Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO)

Role: lead

NCT01018563Phase 2Terminated

An Open Label Extension Study of the Efficacy of MORAb-003

Role: lead

NCT01218516Phase 2Completed

A Safety and Efficacy Study of Farletuzumab in Participants With Adenocarcinoma of the Lung

Role: lead

NCT02357147Phase 2Terminated

Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM)

Role: lead

NCT01574716Phase 2Completed

Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation

Role: lead

NCT00738699Phase 2Terminated

An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer

Role: lead

NCT01521325Phase 1Completed

A Single-Dose Pilot Study of Radiolabeled Amatuximab (MORAb-009) in Mesothelin Over Expressing Cancers

Role: lead

NCT01748721Phase 1Completed

MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Role: lead

NCT01357759Phase 1Completed

Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects

Role: lead

NCT00318370Phase 2Completed

Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy

Role: lead

NCT00570713Phase 2Completed

An Efficacy Study of MORAb-009 in Subjects With Pancreatic Cancer

Role: lead

NCT01123304Phase 1Terminated

Safety Study of Human IgM (MORAb-028) to Treat Metastatic Melanoma

Role: lead

NCT01004380Phase 1Completed

Safety Study of Farletuzumab, Carboplatin and Pegylated Liposomal Doxorubicin (PLD) to Treat Platinum-sensitive Ovarian Cancer

Role: lead

NCT00325494Phase 1Completed

A Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer

Role: lead

NCT01212276Phase 1Terminated

A Safety and MORAb-028 Dose Determination Study in Subjects With Metastatic Melanoma

Role: lead

NCT00847054Phase 1Completed

A Study of of MORAb-004 in Subjects With Solid Tumors

Role: lead

NCT00428766Phase 1Completed

Safety, Tolerability and Pharmacokinetics of MORAb-003 in Subjects With Advanced Ovarian Cancer

Role: lead