Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

11.4%

12 terminated/withdrawn out of 105 trials

Success Rate

87.8%

+1.3% vs industry average

Late-Stage Pipeline

10%

11 trials in Phase 3/4

Results Transparency

71%

61 of 86 completed trials have results

Key Signals

1 recruiting61 with results9 terminated

Enrollment Performance

Analytics

Phase 1

64(66.7%)

Phase 2

19(19.8%)

Phase 3

9(9.4%)

Phase 4

2(2.1%)

N/A

2(2.1%)

96Total

Phase 1(64)

Phase 2(19)

Phase 3(9)

Phase 4(2)

+1 more

Activity Timeline

Global Presence

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Clinical Trials (105)

Showing 20 of 105 trials

NCT06558643Phase 1Completed

Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants

Role: lead

NCT07548021Phase 1Not Yet Recruiting

Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in Rwanda

Role: lead

NCT05361486Completed

Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

Role: lead

NCT06806956Enrolling By Invitation

Severe Malaria in Remote Areas- Closing the Evidence Gap

Role: collaborator

NCT05085340Completed

MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention

Role: collaborator

NCT07362498Completed

Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western Kenya

Role: collaborator

NCT05879224Not ApplicableCompleted

Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia

Role: collaborator

NCT04300309Phase 2Terminated

Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria

Role: collaborator

NCT05979207Phase 1Completed

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

Role: lead

NCT05874271Not ApplicableCompleted

Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea

Role: collaborator

NCT04532931Phase 2Completed

Four Different Experimental Drug Regimens to Standard of Care for the Treatment of Symptomatic Outpatients With COVID-19

Role: collaborator

NCT07011511Phase 1Recruiting

Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy Participants

Role: lead

NCT05287893Phase 1Completed

Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria

Role: lead

NCT05930782Phase 1Completed

Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers.

Role: lead

NCT05507970Phase 1Completed

First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367

Role: lead

NCT05205941Phase 1Completed

MMV533 Plasmodium Falciparum Volunteer Infection Study