Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

21.7%

13 terminated/withdrawn out of 60 trials

Success Rate

75.5%

-11.1% vs industry average

Late-Stage Pipeline

32%

19 trials in Phase 3/4

Results Transparency

10%

4 of 40 completed trials have results

Key Signals

4 recruiting4 with results9 terminated4 withdrawn

Enrollment Performance

Analytics

N/A
19(46.3%)
Phase 4
12(29.3%)
Phase 3
7(17.1%)
Phase 2
3(7.3%)
41Total
N/A(19)
Phase 4(12)
Phase 3(7)
Phase 2(3)

Activity Timeline

Global Presence

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Clinical Trials (60)

Showing 20 of 60 trials
NCT04950894Not ApplicableCompleted

Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

Role: lead

NCT05952674Not ApplicableRecruiting

Treatment Resistant Depression and Vagus Nerve Stimulation

Role: collaborator

NCT03887715Not ApplicableRecruiting

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Role: lead

NCT02751021Not ApplicableCompleted

Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction

Role: collaborator

NCT04779814Terminated

Non-interventional Study Describing Healthcare Resource Utilisation and Clinical Outcomes Associated With VNS Therapy in UK.

Role: lead

NCT03320304Recruiting

A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression.

Role: lead

NCT04753385Terminated

The RECOVER sUb-study, Which Leverages quaNtitative and Credible Research tOols From Verily, Will providE Assessment measuRes for Depressive Episodes

Role: lead

NCT01293526Not ApplicableWithdrawn

Acute Optimization of Cardiac Resynchronization Therapy (CRT)Using Echocardiography and SonR

Role: collaborator

NCT05975931Terminated

IMPACT of AspireSR® for VNS Therapy on Healthcare Resource Utilisation and Clinical Outcomes.

Role: lead

NCT03953768Not ApplicableRecruiting

VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

Role: collaborator

NCT03529045Completed

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

Role: lead

NCT01185392Completed

European Cardiac Resynchronisation Therapy Survey

Role: collaborator

NCT03200574Not ApplicableCompleted

Behavior of Valve Leaflets Following Aortic Valve Implant

Role: collaborator

NCT02263859Not ApplicableCompleted

Targeted Hypoglossal Neurostimulation Study #3

Role: collaborator

NCT03425422Not ApplicableTerminated

ANTHEM-HFrEF Pivotal Study

Role: lead

NCT01987635Not ApplicableCompleted

Assessment of Sustained Systolic-to-diastolic Flexibility of the Mitral Valve Annulus With the Sorin MEMO 3D Mitral Anuloplasty Ring

Role: collaborator

NCT03446664Not ApplicableCompleted

Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study

Role: lead

NCT04282681Withdrawn

XLTCS - Accelerometer Data Collection in an Epilepsy Monitoring Unit (EMU)

Role: lead

NCT02351726Not ApplicableTerminated

Mitroflow DL Post Approval Study- North America

Role: lead

NCT02650232Not ApplicableCompleted

Pilot Study to Evaluate the Somnotouch Device to Quantify Spontaneous Baroreflex Sensitivity

Role: collaborator