Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

10.9%

116 terminated/withdrawn out of 1063 trials

Success Rate

86.4%

-0.1% vs industry average

Late-Stage Pipeline

22%

239 trials in Phase 3/4

Results Transparency

40%

296 of 740 completed trials have results

Key Signals

80 recruiting296 with results85 terminated31 withdrawn

Enrollment Performance

Analytics

Phase 1
443(48.0%)
Phase 3
223(24.2%)
Phase 2
221(24.0%)
Early Phase 1
17(1.8%)
Phase 4
16(1.7%)
N/A
2(0.2%)
922Total
Phase 1(443)
Phase 3(223)
Phase 2(221)
Early Phase 1(17)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (1063)

Showing 20 of 1063 trials
NCT07582783Recruiting

A Study of Persistence to Guselkumab Treatment in Participants With Moderate-to-Severe Plaque Psoriasis in Romania

Role: lead

NCT06663332Phase 3Recruiting

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Role: lead

NCT06532032Phase 1Completed

A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With Metastatic Non-small Cell Lung Cancer

Role: lead

NCT07589634Phase 2Not Yet Recruiting

A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma

Role: lead

NCT05455320Phase 3Active Not Recruiting

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Role: lead

NCT05528510Phase 3Active Not Recruiting

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Role: lead

NCT07577856Phase 3Recruiting

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis

Role: lead

NCT03451851Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

Role: lead

NCT04811560Phase 1Recruiting

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

Role: lead

NCT05663866Phase 2Active Not Recruiting

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Role: lead

NCT05242484Phase 2Active Not Recruiting

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Role: lead

NCT04988295Phase 3Active Not Recruiting

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Role: lead

NCT05242471Phase 2Active Not Recruiting

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Role: lead

NCT07586202Phase 2Not Yet Recruiting

A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLC

Role: lead

NCT03301220Phase 3Completed

A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma

Role: lead

NCT06095115Phase 3Active Not Recruiting

A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis

Role: lead

NCT04176718Phase 2Active Not Recruiting

Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM

Role: collaborator

NCT03390504Phase 3Active Not Recruiting

A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

Role: lead

NCT05388669Phase 3Active Not Recruiting

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

Role: lead

NCT04557098Phase 2Active Not Recruiting

A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Role: lead