Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

7.1%

1 terminated/withdrawn out of 14 trials

Success Rate

92.3%

+5.8% vs industry average

Late-Stage Pipeline

36%

5 trials in Phase 3/4

Results Transparency

50%

6 of 12 completed trials have results

Key Signals

6 with results

Enrollment Performance

Analytics

Phase 1
6(46.2%)
Phase 3
5(38.5%)
Phase 2
2(15.4%)
13Total
Phase 1(6)
Phase 3(5)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT02547870Phase 1Completed

A Study to Evaluate the Pharmacokinetic Effects of Different Storage Conditions for a Long-Acting Nanosuspension of Rilpivirine on Pharmacokinetics

Role: lead

NCT01464762Unknown

Early Access of TMC207 in Patients With Extensively Drug Resistant or Pre-XDR Pulmonary Tuberculosis

Role: lead

NCT02114177Phase 3Completed

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Chronic Hepatitis C Virus Infection Without Cirrhosis

Role: lead

NCT02114151Phase 3Completed

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Genotype 1 Chronic Hepatitis C Virus Infection and Cirrhosis

Role: lead

NCT01600963Phase 3Withdrawn

A Study to Evaluate the Efficacy and Safety of TMC207 in Patients With Pulmonary Infection With Multi-drug Resistant Mycobacterium Tuberculosis

Role: lead

NCT02418559Phase 1Completed

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of JNJ-63623872 in Healthy Japanese Adult Participants

Role: lead

NCT00910871Phase 2Completed

To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.

Role: lead

NCT02262715Phase 1Completed

A Study to Assess the Drug-Drug Interaction Between VX-787 and Oseltamivir

Role: lead

NCT01241760Phase 3Completed

VX-950-C211 - A Dosing Regimen Study (Twice Daily Versus Every 8 Hours) of Telaprevir in Treatment-naïve Participants With Genotype 1 Chronic Hepatitis C Virus Infection

Role: lead

NCT00449644Phase 2Completed

TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB).

Role: lead

NCT01803373Phase 1Completed

A Study to Assess the Relative Bioavailability of TMC207 Following Single-Dose Administrations of Two Pediatric Formulations in Healthy Adult Participants

Role: lead

NCT01600976Phase 1Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Role: lead

NCT01635829Phase 1Completed

A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and Telaprevir

Role: lead

NCT01054573Phase 3Completed

VX-950-TiDP24-C219: A Roll Over Trial for Patients in the Control Group of the C216 Study Who Received Telaprevir Placebo

Role: lead

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