Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

30.8%

4 terminated/withdrawn out of 13 trials

Success Rate

33.3%

-53.2% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

150%

3 of 2 completed trials have results

Key Signals

4 recruiting3 with results

Enrollment Performance

Analytics

Phase 2
7(53.8%)
Phase 1
4(30.8%)
Early Phase 1
2(15.4%)
13Total
Phase 2(7)
Phase 1(4)
Early Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (13)

Showing 13 of 13 trials
NCT05669001Phase 2Completed

A Study of TCD601 in de Novo Renal Transplant Recipients

Role: lead

NCT06453668Phase 1Recruiting

A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

Role: lead

NCT06365437Phase 2Terminated

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Role: lead

NCT06078696Phase 1Terminated

Siplizumab for Sickle Cell Disease Transplant

Role: collaborator

NCT04803058Phase 2Active Not Recruiting

A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE)

Role: lead

NCT04803006Phase 2Terminated

A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA)

Role: lead

NCT05900401Phase 1Active Not Recruiting

Delayed Tolerance Through Mixed Chimerism

Role: collaborator

NCT06455280Phase 1Recruiting

A Study of SIPLIZUMAB in AILD and LT Patients

Role: collaborator

NCT06972069Early Phase 1Recruiting

Tolerance Through Mixed Chimerism (Sip-Tego)

Role: collaborator

NCT06025110Phase 2Terminated

A Study of TCD601 (Siplizumab) in New Onset Type 1 Diabetes Patients

Role: lead

NCT06326476Early Phase 1Recruiting

An Open-label, Time-lagged, Dose-escalation Study to Evalaute the Safety and Efficacy of Subcutaneous Siplizumab in the Treatment of Hidradenitis Suppurativa.

Role: collaborator

NCT04311632Phase 2Completed

A Dose Escalation Study in de Novo Renal Transplantation

Role: lead

NCT06019507Phase 2Active Not Recruiting

A Study of TCD601 in the Induction of Tolerance in de Novo Liver Transplantation

Role: lead

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