Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

22.9%

104 terminated/withdrawn out of 455 trials

Success Rate

64.1%

-22.4% vs industry average

Late-Stage Pipeline

16%

75 trials in Phase 3/4

Results Transparency

98%

182 of 186 completed trials have results

Key Signals

96 recruiting182 with results85 terminated19 withdrawn

Enrollment Performance

Analytics

Phase 2
180(41.3%)
Phase 1
174(39.9%)
Phase 3
72(16.5%)
Early Phase 1
4(0.9%)
Phase 4
3(0.7%)
N/A
3(0.7%)
436Total
Phase 2(180)
Phase 1(174)
Phase 3(72)
Early Phase 1(4)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (455)

Showing 20 of 455 trials
NCT03681561Phase 1Recruiting

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

Role: collaborator

NCT07425054Phase 2Not Yet Recruiting

ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer

Role: collaborator

NCT04463771Phase 2Completed

Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.

Role: lead

NCT05561985Unknown

Expanded Access Use of Itacitinib to Treat a Single Patient With STAT1 Gain of Function (GOF) Disease

Role: lead

NCT07623200Phase 3Not Yet Recruiting

A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

Role: lead

NCT07522073Phase 3Recruiting

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

Role: lead

NCT07448155Phase 1Active Not Recruiting

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of INCA033989 Following Subcutaneous or Intravenous Administration in Healthy Adult Participants

Role: lead

NCT05723055Phase 2Active Not Recruiting

Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

Role: collaborator

NCT05949632Phase 1Terminated

A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

Role: lead

NCT07252050Phase 1Recruiting

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

Role: collaborator

NCT07588139Phase 1Recruiting

A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants

Role: lead

NCT07124078Phase 2Recruiting

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

Role: lead

NCT07104565Phase 2Recruiting

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

Role: lead

NCT07023627Phase 2Recruiting

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Role: lead

NCT06585774Phase 3Recruiting

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Role: lead

NCT06855498Phase 3Recruiting

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

Role: lead

NCT07284849Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Role: lead

NCT07214779Phase 3Recruiting

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Role: lead

NCT07441694Phase 1Recruiting

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

Role: lead

NCT06516952Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)

Role: lead