Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

17.6%

3 terminated/withdrawn out of 17 trials

Success Rate

62.5%

-24.0% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

80%

4 of 5 completed trials have results

Key Signals

6 recruiting4 with results

Enrollment Performance

Analytics

N/A
9(100.0%)
9Total
N/A(9)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT05064709Not ApplicableRecruiting

Assessment of CCM in HF With Higher Ejection Fraction

Role: lead

NCT07112924Recruiting

CCM OPEN HF Registry

Role: lead

NCT07209098Recruiting

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

Role: lead

NCT03970343Active Not Recruiting

Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

Role: lead

NCT05855135Not ApplicableActive Not Recruiting

Assessment of Combined CCM and ICD Device in HFrEF

Role: lead

NCT06973902Recruiting

The Predictive Value of Dobutamine Echo-stress in the Clinical Response to CCM Therapy in Advanced HF

Role: collaborator

NCT06580392Recruiting

CCM and Implementation of Guideline-Directed Medical Therapy in Patients With Heart Failure (Fix-GDMT-HF)

Role: lead

NCT05519046Not ApplicableRecruiting

Cardiac Contractility Modulation in Chagas Heart Disease

Role: collaborator

NCT05704426Terminated

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

Role: collaborator

NCT03240237Not ApplicableCompleted

CCM in Heart Failure With Preserved Ejection Fraction

Role: lead

NCT04755569Unknown

Optimizer System With ODOCOR II CCM™ Leads

Role: lead

NCT03102437Not ApplicableTerminated

Continued Access Protocol for the Evaluation of the OPTIMIZER Smart System

Role: lead

NCT01381172Not ApplicableCompleted

Evaluate Safety and Efficacy of the OPTIMIZER® System in Subjects With Moderate-to-Severe Heart Failure: FIX-HF-5C

Role: lead

NCT02857309Not ApplicableTerminated

Cardiac Contractility Modulation (CCM) Therapy in Subjects With Medically Refractory Heart Failure

Role: lead

NCT00112125Not ApplicableCompleted

Evaluation of the Safety and Effectiveness of the OPTIMIZER System in Subjects With Heart Failure: FIX-HF-5

Role: lead

NCT03339310Not ApplicableCompleted

Evaluation of the Safety and Efficacy of the 2-lead OPTIMIZER® Smart System

Role: lead

NCT02895048Completed

Effects of CCM-therapy in Patients With Heart Failure

Role: collaborator

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