Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

0.0%

0 terminated/withdrawn out of 17 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

18%

3 trials in Phase 3/4

Results Transparency

7%

1 of 15 completed trials have results

Key Signals

2 recruiting1 with results

Enrollment Performance

Analytics

Phase 1
13(76.5%)
Phase 3
2(11.8%)
Phase 4
1(5.9%)
Phase 2
1(5.9%)
17Total
Phase 1(13)
Phase 3(2)
Phase 4(1)
Phase 2(1)

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (17)

Showing 17 of 17 trials
NCT07568678Phase 1Recruiting

A Phase 1, Multiple Ascending Dose Study to Evaluate HMS1005 in Participants With Type 2 Diabetes

Role: lead

NCT06498284Phase 1Completed

Evaluate HM-002-1005 in Subjects With Type 2 Diabetes Mellitus

Role: lead

NCT03790787Phase 1Completed

Drug Interaction Study Between Dorzagliatin and Empagliflozin

Role: lead

NCT06263348Phase 4Recruiting

A Post-Marketing Safety Study of Dorzagliatin in Patients With Type 2 Diabetes

Role: lead

NCT03790839Phase 1Completed

Drug Interaction Study Between Dorzagliatin and Sitagliptin

Role: lead

NCT04426708Phase 1Completed

A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers

Role: lead

NCT03141073Phase 3Completed

Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects

Role: lead

NCT03173391Phase 3Completed

Long-term Efficacy and Safety of HMS5552 in T2DM Subjects

Role: lead

NCT04324424Phase 1Completed

A Clinical Study to Access the Pharmacokinetics of HMS5552 in Renal Impaired Subjects and Healthy Volunteers

Role: lead

NCT02561338Phase 2Completed

A Multi-center 12-week Study of HMS5552 in T2DM

Role: lead

NCT04080596Phase 1Completed

DDI Study to Investigate the Impact of Itraconazole on the Pharmacokinetics of Dorzagliatin

Role: lead

NCT04080609Phase 1Completed

DDI Study Between Dorzagliatin and Rifampicin

Role: lead

NCT03158506Phase 1Completed

Human Mass Balance Study of HMS5552 in Healthy Subjects

Role: lead

NCT01952535Phase 1Completed

A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral HMS5552 in Healthy Volunteers

Role: lead

NCT02077452Phase 1Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HMS5552 in Patients With Type 2 Diabetes

Role: lead

NCT02597400Phase 1Completed

Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM

Role: lead

NCT02386982Phase 1Completed

Beta Cell Function and Related Pharmacodynamics of HMS5552 in T2DM Patients

Role: lead

All 17 trials loaded