Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

91.7%

+5.2% vs industry average

Late-Stage Pipeline

25%

3 trials in Phase 3/4

Results Transparency

36%

4 of 11 completed trials have results

Key Signals

4 with results

Enrollment Performance

Analytics

Phase 2
6(50.0%)
Phase 3
3(25.0%)
Phase 1
3(25.0%)
12Total
Phase 2(6)
Phase 3(3)
Phase 1(3)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT06415773Phase 3Completed

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Role: lead

NCT06350890Phase 3Completed

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes

Role: lead

NCT06353347Phase 3Completed

Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Role: lead

NCT03333928Phase 2Completed

A POC and Dose-Ranging Study of HTD1801 in PSC Patients

Role: lead

NCT05623189Phase 2Completed

HTD1801 in Adults With Nonalcoholic Steatohepatitis and Liver Fibrosis Who Have Type 2 Diabetes or Pre-Diabetes

Role: lead

NCT06411275Phase 2Completed

A Phase 2 Study of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Diet and Exercise

Role: lead

NCT04604652Phase 2Completed

Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis

Role: lead

NCT03381287Phase 1Completed

A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia

Role: lead

NCT03656744Phase 2Completed

A Study of HTD1801 in Adults With Nonalcoholic Steatohepatitis (NASH) and Type 2 Diabetes Mellitus (T2DM)

Role: lead

NCT03678480Phase 2Withdrawn

A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)

Role: lead

NCT02538848Phase 1Completed

Study of HTD4010 in Healthy Volunteers

Role: lead

NCT03099603Phase 1Completed

A Study of HTD1801 in Healthy Subjects

Role: lead

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