Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

16.6%

196 terminated/withdrawn out of 1182 trials

Success Rate

79.1%

-7.4% vs industry average

Late-Stage Pipeline

33%

386 trials in Phase 3/4

Results Transparency

69%

514 of 740 completed trials have results

Key Signals

83 recruiting514 with results160 terminated36 withdrawn

Enrollment Performance

Analytics

Phase 2
333(32.3%)
Phase 3
239(23.2%)
Phase 1
218(21.1%)
Phase 4
147(14.3%)
N/A
91(8.8%)
Early Phase 1
3(0.3%)
1031Total
Phase 2(333)
Phase 3(239)
Phase 1(218)
Phase 4(147)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (1182)

Showing 20 of 1182 trials
NCT07178730Phase 3Not Yet Recruiting

NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancer

Role: collaborator

NCT04647916Phase 2Active Not Recruiting

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

Role: collaborator

NCT07560046Phase 4Not Yet Recruiting

Combating Related Epidemics in HCV

Role: collaborator

NCT06477419Phase 2Recruiting

A Study of Sacituzumab Govitecan in People With Mesothelioma

Role: collaborator

NCT02842086Phase 3Active Not Recruiting

Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex With Men and Are At Risk of HIV-1 Infection

Role: lead

NCT07473778Recruiting

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

Role: lead

NCT03301506Phase 3Active Not Recruiting

Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

Role: lead

NCT04950764Phase 1Completed

An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)

Role: lead

NCT05143229Phase 1Active Not Recruiting

Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer

Role: collaborator

NCT04736173Phase 2Active Not Recruiting

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Role: collaborator

NCT06682728Phase 2Recruiting

Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma at High-Risk Recurrence

Role: collaborator

NCT06051617Phase 3Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Role: lead

NCT06964113Phase 4Recruiting

A Study of Filgotinib 200 mg in Korean Participants With Moderately to Severely Active Ulcerative Colitis Under Routine Clinical Practice

Role: collaborator

NCT05633654Phase 3Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

Role: lead

NCT06630286Phase 3Active Not Recruiting

Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1

Role: lead

NCT04468061Phase 2Recruiting

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

Role: collaborator

NCT05329766Phase 2Active Not Recruiting

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Role: collaborator

NCT07096193Phase 1Recruiting

Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus

Role: lead

NCT07031219Not ApplicableNot Yet Recruiting

HIV/HBV/HCV Triple Screening in Primary Care

Role: collaborator

NCT06801834Phase 3Recruiting

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

Role: lead