Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

22.8%

21 terminated/withdrawn out of 92 trials

Success Rate

44.7%

-41.8% vs industry average

Late-Stage Pipeline

16%

15 trials in Phase 3/4

Results Transparency

124%

21 of 17 completed trials have results

Key Signals

29 recruiting21 with results19 terminated

Enrollment Performance

Analytics

Phase 1
44(49.4%)
Phase 2
30(33.7%)
Phase 3
13(14.6%)
Phase 4
2(2.2%)
89Total
Phase 1(44)
Phase 2(30)
Phase 3(13)
Phase 4(2)

Activity Timeline

Global Presence

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Clinical Trials (92)

Showing 20 of 92 trials
NCT07384715Phase 1Recruiting

First-in-human (FIH) Trial of GEN3018 in Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) or Higher-risk Myelodysplastic Syndrome (HR-MDS)

Role: lead

NCT05852717Phase 2Recruiting

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

Role: collaborator

NCT07539311Phase 2Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced Gastrointestinal (GI) Cancers

Role: lead

NCT04083599Phase 1Active Not Recruiting

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Role: lead

NCT05283720Phase 2Recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Role: lead

NCT06191744Phase 3Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Role: lead

NCT07166094Phase 3Recruiting

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

Role: lead

NCT07225270Phase 3Recruiting

Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy

Role: lead

NCT07226752Phase 3Active Not Recruiting

A Sub-study Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL) in China

Role: lead

NCT03625037Phase 1Active Not Recruiting

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Role: lead

NCT04628494Phase 3Active Not Recruiting

A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)

Role: lead

NCT05848765Phase 2Recruiting

Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

Role: collaborator

NCT04663347Phase 1Active Not Recruiting

Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)

Role: lead

NCT06635824Phase 3Active Not Recruiting

Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)

Role: lead

NCT04623541Phase 1Active Not Recruiting

Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome

Role: lead

NCT06057038Phase 1Active Not Recruiting

A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors

Role: lead

NCT06984328Phase 2Active Not Recruiting

Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)

Role: lead

NCT05660967Phase 2Active Not Recruiting

Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma

Role: lead

NCT07288177Phase 2Recruiting

Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

Role: lead

NCT04542824Phase 1Active Not Recruiting

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)

Role: lead