Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

23.1%

3 terminated/withdrawn out of 13 trials

Success Rate

76.9%

-9.6% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

10%

1 of 10 completed trials have results

Key Signals

1 with results

Enrollment Performance

Analytics

Phase 1
7(53.8%)
Phase 2
6(46.2%)
13Total
Phase 1(7)
Phase 2(6)

Activity Timeline

Global Presence

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Clinical Trials (13)

Showing 13 of 13 trials
NCT00427856Phase 2Completed

Safety and Efficacy of Single Agent Obatoclax Mesylate (GX15-070MS) Followed by a Combination With Rituximab for Previously-untreated Follicular Lymphoma (FL)

Role: lead

NCT00724841Phase 1Terminated

A Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic Melanoma

Role: lead

NCT00682981Phase 1Completed

A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC)

Role: lead

NCT00407303Phase 1Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in Combination With Bortezomib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma (MCL)

Role: lead

NCT00405951Phase 1Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS)in Combination With Docetaxel for the Treatment of Non-Small Cell Lung Cancer

Role: lead

NCT00600964Phase 1Completed

A Phase I/II Study of GX15-070MS in Untreated CLL

Role: lead

NCT00438178Phase 1Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) for the Treatment of Hematological Malignancies

Role: lead

NCT00457574Phase 1Withdrawn

Safety and Efficacy of GMX1777 in the Treatment of Refractory Solid Tumors or Lymphomas

Role: lead

NCT00360035Phase 2Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in the Treatment of Myelofibrosis With Myeloid Metaplasia

Role: lead

NCT00413114Phase 2Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS)for the Treatment of Myelodysplastic Syndromes (MDS)

Role: lead

NCT00684918Phase 2Completed

Study of Obatoclax in Previously Untreated Acute Myeloid Leukemia (AML)

Role: lead

NCT00359892Phase 2Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in the Treatment of Hodgkin's Lymphoma

Role: lead

NCT00918931Phase 2Terminated

Obatoclax for Systemic Mastocytosis

Role: collaborator

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