Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

13.5%

5 terminated/withdrawn out of 37 trials

Success Rate

79.2%

-7.3% vs industry average

Late-Stage Pipeline

16%

6 trials in Phase 3/4

Results Transparency

74%

14 of 19 completed trials have results

Key Signals

4 recruiting14 with results

Enrollment Performance

Analytics

Phase 2
10(38.5%)
N/A
6(23.1%)
Phase 3
5(19.2%)
Phase 1
4(15.4%)
Phase 4
1(3.8%)
26Total
Phase 2(10)
N/A(6)
Phase 3(5)
Phase 1(4)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (37)

Showing 20 of 37 trials
NCT05457257Phase 4Active Not Recruiting

Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations

Role: collaborator

NCT05197322Phase 2Recruiting

NEOadjuvant PembRolizumab In Stratified Medicine - ColoRectal Cancer

Role: collaborator

NCT06745882Phase 2Recruiting

Prospective Trial Assessing Real World Outcomes Response to Pembro in Black Patients w/ NSCLC

Role: collaborator

NCT04486352Phase 1Recruiting

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

Role: collaborator

NCT02780128Phase 1Terminated

Next Generation Personalized Neuroblastoma Therapy

Role: collaborator

NCT00578240Active Not Recruiting

Molecular Studies and Clinical Correlations in Human Prostatic Disease

Role: collaborator

NCT05062889Phase 2Suspended

Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients

Role: collaborator

NCT05846594Not ApplicableCompleted

A Study to Evaluate the Impact of Liquid Biopsy in Participants With a Clinical Diagnosis of Advanced Cancer

Role: collaborator

NCT03498521Phase 2Completed

A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site

Role: collaborator

NCT06146920Not ApplicableActive Not Recruiting

Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation

Role: collaborator

NCT02975934Phase 3Completed

A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

Role: collaborator

NCT02965755Not ApplicableActive Not Recruiting

Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins

Role: collaborator

NCT03522246Phase 3Active Not Recruiting

A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy

Role: collaborator

NCT04849364Phase 2Terminated

Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer

Role: collaborator

NCT04504604Not ApplicableRecruiting

TCF-001 TRACK (Target Rare Cancer Knowledge) Study

Role: collaborator

NCT02795156Phase 2Completed

Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations

Role: collaborator

NCT02987543Phase 3Completed

Study of Olaparib (Lynparza™) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study)

Role: collaborator

NCT03824704Phase 2Terminated

A Study to Evaluate Rucaparib in Combination With Nivolumab in Patients With Selected Solid Tumors (ARIES)

Role: collaborator

NCT01891344Phase 2Completed

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)

Role: collaborator

NCT02855944Phase 3Completed

ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

Role: collaborator