Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

27.3%

3 terminated/withdrawn out of 11 trials

Success Rate

62.5%

-24.0% vs industry average

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

80%

4 of 5 completed trials have results

Key Signals

2 recruiting4 with results

Enrollment Performance

Analytics

Phase 1
6(54.5%)
Phase 2
4(36.4%)
Phase 3
1(9.1%)
11Total
Phase 1(6)
Phase 2(4)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT06198712Phase 2Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

Role: lead

NCT04987489Phase 2Completed

A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease

Role: lead

NCT04624659Phase 3Active Not Recruiting

A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)

Role: lead

NCT05568225Phase 2Terminated

A Study of Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS)

Role: lead

NCT04004325Phase 1Terminated

A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis

Role: lead

NCT05953584Phase 2Recruiting

A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke

Role: lead

NCT02719574Phase 1Completed

Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation

Role: lead

NCT03815695Phase 1Completed

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Role: lead

NCT02543879Phase 1Completed

Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies

Role: lead

NCT03684811Phase 1Completed

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Role: lead

NCT04013880Phase 1Withdrawn

ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Role: collaborator

All 11 trials loaded