Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

26.7%

4 terminated/withdrawn out of 15 trials

Success Rate

69.2%

-17.3% vs industry average

Late-Stage Pipeline

27%

4 trials in Phase 3/4

Results Transparency

11%

1 of 9 completed trials have results

Key Signals

1 with results

Enrollment Performance

Analytics

Phase 2
6(42.9%)
Phase 4
4(28.6%)
Phase 1
3(21.4%)
N/A
1(7.1%)
14Total
Phase 2(6)
Phase 4(4)
Phase 1(3)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (15)

Showing 15 of 15 trials
NCT00406107Phase 4Completed

Evaluation of Macugen Treatment of Macular Edema Due to Branch Retinal Vein Occlusion

Role: collaborator

NCT01487044Unknown

A Single-Center Trial of High Frequency Pegaptanib for Rapid Restoration of VEGF Levels in Diabetic Retinal Edema

Role: collaborator

NCT00295828Phase 1Completed

A Pilot Study for the Treatment of Iris Neovascularization With Macugen

Role: collaborator

NCT00346983Phase 1Terminated

Macugen to Prevent Worsening of Macular Edema Following Cataract Surgery in Diabetics

Role: collaborator

NCT00358423Phase 1Terminated

The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema

Role: collaborator

NCT00088283Phase 2Completed

Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)

Role: lead

NCT00134667Phase 4Terminated

Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)

Role: lead

NCT00312351Phase 4Terminated

A Clinical Trial to Explore the Safety and Efficacy of Three Different Doses of Pegaptanib Sodium in Patients With Wet Age-Related Macular Degeneration (AMD)

Role: lead

NCT00354445Phase 4Unknown

A Clinical Trial to Explore the Safety and Efficacy of Injections of Macugen When Given Every 6 Weeks in Subjects With AMD

Role: lead

NCT00321997Phase 2Completed

A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.

Role: lead

NCT00215670Phase 2Completed

Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)

Role: lead

NCT00087763Phase 2Completed

Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)

Role: lead

NCT00040313Phase 2Completed

Pegaptanib Sodium Compared to Sham Injection in Patients With DME Involving the Center of the Macula

Role: lead

NCT00088192Not ApplicableCompleted

Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD)

Role: lead

NCT00021736Phase 2Completed

Phase II/III Study of Anti-VEGF in Neovascular AMD

Role: lead

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