Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

20.6%

87 terminated/withdrawn out of 422 trials

Success Rate

72.0%

-14.5% vs industry average

Late-Stage Pipeline

40%

168 trials in Phase 3/4

Results Transparency

10%

23 of 224 completed trials have results

Key Signals

20 recruiting23 with results61 terminated26 withdrawn

Enrollment Performance

Analytics

Phase 3
167(43.5%)
Phase 2
161(41.9%)
Phase 1
38(9.9%)
N/A
17(4.4%)
Phase 4
1(0.3%)
384Total
Phase 3(167)
Phase 2(161)
Phase 1(38)
N/A(17)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (422)

Showing 20 of 422 trials
NCT02446444Phase 3Active Not Recruiting

Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer

Role: collaborator

NCT05815927Phase 3Recruiting

Pembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer

Role: lead

NCT02834884Recruiting

SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access

Role: lead

NCT01244789Phase 2Active Not Recruiting

Chemotherapy or Observation in Stage I-II Intermediate or High Risk Endometrial Cancer

Role: collaborator

NCT07522762Recruiting

Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational Study

Role: collaborator

NCT04031677Phase 3Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

Role: lead

NCT06809322Phase 3Recruiting

Vorasidenib Maintenance for IDH Mutant Astrocytoma

Role: lead

NCT04685616Phase 3Recruiting

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

Role: collaborator

NCT00003140Phase 3Completed

Letrozole After Tamoxifen in Treating Women With Breast Cancer

Role: collaborator

NCT02504372Phase 3Completed

Study of Pembrolizumab (MK-3475) vs Placebo for Participants With Non-small Cell Lung Cancer After Resection With or Without Standard Adjuvant Therapy (MK-3475-091/KEYNOTE-091)

Role: collaborator

NCT03590171Phase 2Recruiting

International Study for Treatment of High Risk Childhood Relapsed ALL 2010

Role: collaborator

NCT06246149Phase 3Recruiting

Adjuvant Tebentafusp in High Risk Ocular Melanoma

Role: lead

NCT06219317Phase 2Recruiting

Immunotherapy Consolidation After Radical Treatment of Synchronous Oligo-metastatic NSCLC

Role: lead

NCT07425808Phase 2Not Yet Recruiting

FLT3-ITD Targeted Therapy in Fit AML Patients

Role: lead

NCT05904119Phase 3Recruiting

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

Role: lead

NCT02394626Phase 2Recruiting

Surgery for Recurrent Glioblastoma

Role: collaborator

NCT02492607Not ApplicableActive Not Recruiting

Management of Low-risk (Grade I and II) DCIS

Role: collaborator

NCT05259605Recruiting

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Role: lead

NCT03224104Phase 1Completed

Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma.

Role: lead

NCT07234877Phase 2Not Yet Recruiting

A Randomized Phase II Study Evaluating Upfront SRT to All Brain Metastases Followed by Ivonescimab Plus Chemotherapy Versus Upfront Ivonescimab Plus Chemotherapy in Patients With Asymptomatic Active Brain Metastases From NSCLC

Role: lead