Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

5.4%

2 terminated/withdrawn out of 37 trials

Success Rate

94.6%

+8.1% vs industry average

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

11%

4 of 35 completed trials have results

Key Signals

4 with results

Enrollment Performance

Analytics

Phase 2
19(76.0%)
Phase 1
4(16.0%)
Phase 3
2(8.0%)
25Total
Phase 2(19)
Phase 1(4)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (37)

Showing 20 of 37 trials
NCT02601690Terminated

Observational Analysis of T Cell Responses to SPIREs for Multiple Allergens in Subjects With Allergy in North America

Role: collaborator

NCT02311413Phase 2Completed

A Randomized Prospective Clinical Trial of Fel d 1 Peptide Immunotherapy

Role: collaborator

NCT02040844Phase 3Completed

Phase III Cat-PAD Follow-on Study

Role: lead

NCT02150343Phase 2Completed

Phase II HDM-SPIRE Safety and Efficacy Study

Role: lead

NCT01620762Phase 3Completed

Phase III Cat-PAD Study

Role: lead

NCT01921257Phase 2Completed

Paediatric Safety Study in Cat-PAD

Role: lead

NCT02478060Phase 2Completed

Birch-SPIRE Safety and Efficacy Study

Role: lead

NCT02795273Phase 2Withdrawn

Efficacy and Safety of Grass-SPIRE Registration Study

Role: lead

NCT02396680Completed

Ragweed-SPIRE Follow-On Study

Role: lead

NCT02075138Completed

Grass Observational Study

Role: lead

NCT02161107Phase 2Completed

Study of Grass-SPIRE in Subjects With Grass Allergies and Asthma

Role: lead

NCT02061709Phase 2Completed

Evaluating the Efficacy of Ragweed-SPIRE Following Exposure to Ragweed Allergen in an Environmental Exposure Chamber

Role: lead

NCT02061670Phase 2Completed

Safety Study of Ragweed-SPIRE in Subjects With Ragweed Allergies and Asthma

Role: lead

NCT02292875Completed

ToleroMune Grass Follow on Study

Role: lead

NCT01383603Phase 1Completed

Identification of Potential Biomarkers of Peptide Immunotherapy. Part 2 - Gene Array Analysis

Role: lead

NCT01949441Phase 2Completed

ToleroMune House Dust Mite (HDM) Tolerability Study

Role: lead

NCT01949415Completed

An Optional Investigation of Biomarkers of Efficacy

Role: lead

NCT01923792Completed

ToleroMune House Dust Mite Follow on Study

Role: lead

NCT01949428Completed

House Dust Mite Observational Study

Role: lead

NCT01383590Phase 1Completed

Identification of Potential Biomarkers of Peptide Immunotherapy. Part 1 - Proteomics Analysis

Role: lead