Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

10.6%

23 terminated/withdrawn out of 216 trials

Success Rate

88.1%

+1.6% vs industry average

Late-Stage Pipeline

38%

81 trials in Phase 3/4

Results Transparency

18%

31 of 170 completed trials have results

Key Signals

12 recruiting31 with results18 terminated5 withdrawn

Enrollment Performance

Analytics

Phase 3
63(33.9%)
Phase 2
55(29.6%)
Phase 1
46(24.7%)
Phase 4
18(9.7%)
N/A
4(2.2%)
186Total
Phase 3(63)
Phase 2(55)
Phase 1(46)
Phase 4(18)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (216)

Showing 20 of 216 trials
NCT00861926Phase 3Completed

Study on Foster Efficacy Maintenance and Reliever vs Foster Maintenance + Salbutamol Reliever in Asthmatics (MART2)

Role: lead

NCT07046442Completed

Effect of Pulmonary Rehabilitation and Physical Activity on COVID-19 Long-Term Symptoms (PuReCOVID)

Role: collaborator

NCT07546981Phase 3Not Yet Recruiting

Efficacy and Safety of CHF 5993 100/6/12.5 μg HFA-152a pMDI in Patients With Asthma Uncontrolled on Medium Doses of Inhaled Corticosteroids in Combination With Long-acting ß2-agonists

Role: lead

NCT02296411Phase 2Completed

Efficacy of LAMA Added to ICS in Treatment of Asthma (ELITRA)

Role: lead

NCT06264674Phase 3Completed

Comparison Between CHF5993 pMDI 200/6/12.5 µg HFA-152a VS CHF5993 pMDI 200/6/12.5 µg HFA-134a in Subjects With Asthma (TRECOS).

Role: lead

NCT02127866Phase 2Completed

Triple in Asthma Dose Finding

Role: lead

NCT04876677Phase 3Completed

Functional Respiratory Imaging Study (DARWiIN)

Role: lead

NCT07516951Phase 2Not Yet Recruiting

A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants With Idiopathic Pulmonary Fibrosis

Role: lead

NCT04886999Phase 3Completed

Study in Adult Patients With Moderate to Severe Asthma

Role: lead

NCT03566017Phase 3Completed

Open Label Extension Study of 1 mg/kg Pegunigalsidase Alfa Every 2 Weeks in Patients With Fabry Disease

Role: lead

NCT06328608Phase 2Recruiting

A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease

Role: lead

NCT07181382Phase 3Suspended

Efficacy and Safety of Seralutinib in Adult Subjects With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Role: collaborator

NCT01577082Phase 3Completed

Efficacy and Safety of CHF 1535 200/6µg in Not Adequately Controlled Asthmatic Patients

Role: lead

NCT06941025Recruiting

Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding

Role: lead

NCT05710692Phase 2Recruiting

Study to Evaluate the Safety, PK, PD, and Efficacy of PRX-102 in Japanese Patients With Fabry Disease

Role: lead

NCT05065424Phase 4Completed

Premedication for Less Invasive Surfactant Administration Study (PRELISA)

Role: collaborator

NCT06166056Phase 1Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Role: lead

NCT04471870Completed

ARCANGELO (itAlian pRospective Study on CANGrELOr)

Role: lead

NCT06746064Phase 1Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF10073 After Single and Multiple Doses in Healthy Volunteers and the Effect of Itraconazole on CHF10073 Exposure

Role: lead

NCT04636814Phase 3Terminated

A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)

Role: lead